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Structure of hepatic acinus

Known as: Hepatic acinus, Liver Acinus, Portal acinus 
The smallest functional unit of the liver, comprising all of the liver parenchyma supplied by a terminal branch of the portal vein and hepatic artery… 
National Institutes of Health

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Hepatic laminaPortal triad
Hepatic lobuleHepatobiliary SystemLiverLiver Acinus Zone 1

Papers overview

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2001
2001
Expression of CYP27A, a gene encoding a vitamin D‐25 hydroxylase in human liver and kidney
Vitamin D3 (D3) is not active but must be hydroxylated at C‐25 in liver before acquiring its hormonal potential in the kidney… 
1999
1999
Distribution of alcohol dehydrogenase isoenzymes in the human liver acinus
Abstract By the use of a newly developed technique of ultrathin-layer electrophoresis, class I and class II alcohol dehydrogenase… 
1996
1996
Pi-class glutathione-S-transferase-positive hepatocytes in aging B6C3F1 mice undergo apoptosis induced by dietary restriction.
Liver sections from aging ad libitum-fed and diet-restricted B6C3F1 male mice were evaluated immunohistochemically for pi-class… 
1991
1991
Microquantitative analysis of the intra-acinar profiles of glutamate dehydrogenase in rat liver.
In adult male and female rat liver, the activity of NAD(+)-and NADP(+)-dependent glutamate dehydrogenase (GDH) was… 
1989
1989
Hepatic zonation of drug metabolizing enzymes. Studies on hepatocytes isolated from the periportal or perivenous region of the liver acinus.
Models of hepatic intraacinar zonation have been proposed previously; in most models, direct visualization of the acinar… 
1989
1989
In situ kinetic parameters of glucose-6-phosphate dehydrogenase and phosphogluconate dehydrogenase in different areas of the rat liver acinus
SummaryThe reaction velocity of glucose-6-phosphate dehydrogenase (G6PDH) and phosphogluconate dehydrogenase (PGDH) was… 
1985
1985
Evidence for lack of promotion of the growth of the common naturally occurring basophilic focal hepatocellular proliferative lesions in aged F344/NCr rats by phenobarbital.
Aged female F344/NCr rats were exposed to phenobarbital (PB), 500 p.p.m. in the drinking water, from 26 months of age, for… 
1983
1983
Distribution of pyruvate kinase type L and M2 in microdissected periportal and perivenous rat liver tissue with different dietary states.
Pyruvate kinase type L and M2 activities were measured in microdissected periportal and perivenous liver tissue from rats in… 
1983
1983
Kinetics of DNA synthesis in feeding-dependent and independent hepatocyte populations of rats after partial hepatectomy.
The effects of food consumption on the kinetics of hepatic DNA synthesis after partial hepatectomy (PH) have been studied in rats… 
1979
1979
Microphotometric determination of enzyme activities in cryostat sections by the gel film technique.
Use of the gel film technique in microphotometric determinations of enzyme activity is described. The microscope photometer is… 
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