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Structure of hepatic acinus

Known as: Hepatic acinus, Liver Acinus, Portal acinus 
The smallest functional unit of the liver, comprising all of the liver parenchyma supplied by a terminal branch of the portal vein and hepatic artery… 
National Institutes of Health

Related topics

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12 relations

Narrower (2)

Hepatic laminaPortal triad
Hepatic lobuleHepatobiliary SystemLiverLiver Acinus Zone 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Expression of CYP27A, a gene encoding a vitamin D‐25 hydroxylase in human liver and kidney
Vitamin D3 (D3) is not active but must be hydroxylated at C‐25 in liver before acquiring its hormonal potential in the kidney… 
Review
1994
Review
1994
Integration of function in the hepatic acinus: intercellular communication in neural and humoral control of liver metabolism.
Highly Cited
1992
Highly Cited
1992
Connexins and glucagon receptors during development of rat hepatic acinus.
Levels (by immunoblotting) and cell distribution (by immunofluorescence) of connexins (Cxs) and glucagon receptors (GRs) were… 
1987
1987
Development of enzymic zonation in liver parenchyma is related to development of acinar architecture.
The appearance of the distribution patterns of the NH3-metabolizing enzymes carbamoylphosphate synthetase, glutamate… 
1987
1987
Phenobarbital induction of cytochrome P-450 in normal and preneoplastic rat liver: comparison of enzyme and mRNA expression as detected by immunohistochemistry and in situ hybridization.
The expression levels of the major phenobarbital-inducible cytochromes P-450 were analyzed immunohistochemically in liver… 
Highly Cited
1986
Highly Cited
1986
The isolation of functionally heterogeneous hepatocytes of the proximal and distal half of the liver acinus in the rat
The objective of this study was to isolate hepatocytes of the proximal half (Zones 1 and 2) or distal half (Zones 2 and 3) of the… 
1986
1986
Heterogeneous expression of phenobarbital‐inducible cytochrome P‐450 genes within the hepatic acinus in the rat
Within the hepatic acinus, the functional unit of liver parenchyma, the induction of cytochrome P‐450 protein by phenobarbital is… 
Highly Cited
1982
Highly Cited
1982
Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver.
The livers from a total of 51 Sprague-Dawley rats treated with different doses of N-nitrosomorpholine (80-120 mg/l in the… 
Highly Cited
1982
Highly Cited
1982
Reciprocal distribution of hexokinase and glucokinase in the periportal and perivenous zone of the rat liver acinus.
Glucokinase and hexokinase activities were measured in the periportal and perivenous zone of the liver acinus separated by… 
Highly Cited
1978
Highly Cited
1978
NADP-dependent dehydrogenases in rat liver parenchyma
SummaryAt present soluble NADP-dependent dehydrogenases are histochemically demonstrated in three different ways: according to… 
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