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Streptozocin

Known as: Estreptozocina, Streptozotocin, N-D-Glucosyl-(2)-n'-nitrosomethylharnstoff 
A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand… 
National Institutes of Health

Related topics

Related topics

27 relations

Narrower (7)

4,6-ethylidene glucose streptozotocinGANUMOF-Strep protocolZanosar
Alkylating Activity [MoA]Colorectal NeoplasmsDrug AllergyFAM-S protocol

Broader (2)

Antibiotics, AntineoplasticNitrosourea Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Functional Characterization of Dehydratase/Aminotransferase Pairs from Helicobacter and Campylobacter
Helicobacter pylori and Campylobacter jejuni have been shown to modify their flagellins with pseudaminic acid (Pse), via O… 
Highly Cited
1994
Highly Cited
1994
The use of 2-deoxy-2-trichloroacetamido-D-glucopyranose derivatives in syntheses of oligosaccharides.
Highly Cited
1983
Highly Cited
1983
Glucose Insensitivity and Amino-acid Hypersensitivity of Insulin Release in Rats with Non-insulin-dependent Diabetes: A Study with the Perfused Pancreas
Non-insulin-dependent diabetes (NIDDM) was obtained in adult rats following a neonatal streptozotocin injection. Rats with NIDDM… 
Highly Cited
1981
Highly Cited
1981
Current knowledge of pancreatic carcinogenesis in the hamster and its relevance to the human disease
Syrian hamsters present a unique species for induction of pancreatic tumors that in many aspects resemble human pancreatic cancer… 
Highly Cited
1981
Highly Cited
1981
A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems.
The effects of insulin-dependent diabetes mellitus on glucose transport activity and on the concentrations of glucose transport… 
Highly Cited
1981
Highly Cited
1981
Impaired Wound Healing in Streptozotocin Diabetes: Prevention by Supplemental Vitamin A
Goodson and Hunt showed that wound healing is impaired in streptozotocin (Sz) diabetic rats; we speculated that this impairment… 
Highly Cited
1979
Highly Cited
1979
CP-45,634: a novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats.
Highly Cited
1978
Highly Cited
1978
Decreased vascular prostacyclin in experimental diabetes.
Highly Cited
1972
Highly Cited
1972
Dependence of hypothalamic obesity on insulin, the pituitary and the adrenal gland.
ABSTRACT. The obesity which follows destruction of the ventromedial nucleus (VMN) of the hypothalamus of rats is accompanied by… 
Highly Cited
1967
Highly Cited
1967
The structure of streptozotocin.
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