Streptozocin

Known as: Estreptozocina, Streptozotocin, N-D-Glucosyl-(2)-n'-nitrosomethylharnstoff 
A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Background:The role of chemotherapy for neuroendocrine tumours remains controversial and there is no standard regimen.Method:We… (More)
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Highly Cited
2008
Highly Cited
2008
Development of a cell therapy for diabetes would be greatly aided by a renewable supply of human β-cells. Here we show that… (More)
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Highly Cited
2004
Highly Cited
2004
Skeletal muscle atrophy is a debilitating response to starvation and many systemic diseases including diabetes, cancer, and renal… (More)
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Highly Cited
2003
Highly Cited
2003
Effects of the intraperitoneal injection of quercetin in streptozocin-induced diabetic and normal rats were investigated and… (More)
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Highly Cited
2001
Highly Cited
2001
Acrp30 is a circulating protein synthesized in adipose tissue. A single injection in mice of purified recombinant Acrp30 leads to… (More)
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Highly Cited
2001
Highly Cited
2001
Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the… (More)
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Highly Cited
1999
Highly Cited
1999
Human type 1 diabetes results from the selective destruction of insulin-producing pancreatic beta cells during islet inflammation… (More)
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Highly Cited
1993
Highly Cited
1993
Painful diabetic neuropathy is one of the most common complications of insulin-dependent diabetes in man. Conflicting results… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND The combination of streptozocin and fluorouracil has become the standard therapy for advanced islet-cell carcinoma… (More)
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Highly Cited
1980
Highly Cited
1980
To evaluate the treatment of advanced islet-cell carcinoma, we randomly assigned 84 patients to streptozocin alone or… (More)
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