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Streptozocin

Known as: Estreptozocina, Streptozotocin, N-D-Glucosyl-(2)-n'-nitrosomethylharnstoff 
A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
  • Z. Shariatinia
  • Advances in colloid and interface science
  • 2019
  • Corpus ID: 56148272
Chitosan (CS) is a linear polysaccharide which is achieved by deacetylation of chitin, which is the second most plentiful… Expand
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Highly Cited
2008
Highly Cited
2008
Development of a cell therapy for diabetes would be greatly aided by a renewable supply of human β-cells. Here we show that… Expand
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Highly Cited
2004
Highly Cited
2004
PURPOSE The role of systemic chemotherapy in the management of pancreatic endocrine carcinoma (islet cell carcinoma; PEC) is an… Expand
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Review
2001
Review
2001
Alloxan and streptozotocin are widely used to induce experimental diabetes in animals. The mechanism of their action in B cells… Expand
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Highly Cited
2001
Highly Cited
2001
Acrp30 is a circulating protein synthesized in adipose tissue. A single injection in mice of purified recombinant Acrp30 leads to… Expand
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Highly Cited
2001
Highly Cited
2001
Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the… Expand
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Highly Cited
1992
Highly Cited
1992
BACKGROUND The combination of streptozocin and fluorouracil has become the standard therapy for advanced islet-cell carcinoma… Expand
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Highly Cited
1987
Highly Cited
1987
We investigated the possible involvement of reactive oxygen radical-related processes in chronic (12-wk) diabetes induced in rats… Expand
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Highly Cited
1980
Highly Cited
1980
To evaluate the treatment of advanced islet-cell carcinoma, we randomly assigned 84 patients to streptozocin alone or… Expand
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Highly Cited
1980
Highly Cited
1980
Single implantation of microencapsulated islets into rats with streptozotocin-induced diabetes corrected the diabetic state for 2… Expand
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