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Steroid 21-Monooxygenase

Known as: Cytochrome P 450 CYP21, hydroxylase 21, 21-hydroxylase 
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH… 
National Institutes of Health

Related topics

Related topics

13 relations
21-Hydroxylase Ab:ACnc:Pt:Ser:QnCYP21A2 geneCongenital adrenal hyperplasiaIn Blood

Narrower (2)

CYP21A2 protein, humanCYP2C5 protein, Oryctolagus cuniculus

Papers overview

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Review
2002
Review
2002
Genital Surgery among Females with Congenital Adrenal Hyperplasia: Changes Over the Past Five Decades
The treatment of intersex patients, including any patient born with genital ambiguity, is being reassessed. The re-evaluation is… 
1997
1997
Impairment of 11β-hydroxylase but not 21-hydroxylase in adrenal 'incidentalomas'
Recent reports have shown an exaggerated response of 17-hydroxyprogesterone in up to 70% of patients with incidentally detected… 
Highly Cited
1987
Highly Cited
1987
Adrenal status during the first month of life in mature and premature human infants.
Measurements of 17-hydroxyprogesterone (17-OHP) in blood collected onto filter paper after heel puncture by lancet and steroid… 
1986
1986
Is heterozygosity for the steroid 21-hydroxylase deficiency responsible for hirsutism, premature pubarche, early puberty, and precocious puberty in children?
We applied the ACTH-stimulation test developed in our laboratory for the detection of heterozygous carriers of the 21-hydroxylase… 
1983
1983
Inborn errors of steroid biosynthesis: detection by a new mass-spectrometric method.
A new mass-spectrometric technique relies on ionization during bombardment of the analyte (dissolved in a liquid matrix, usually… 
1980
1980
Gonadal dysfunction in adult men with congenital adrenal hyperplasia.
Two adult males are described with congenital adrenal hyperplasia (21-hydroxylase deficiency). Patient 1 was receiving therapy… 
1979
1979
17-Hydroxyprogesterone in the cosyntropin test: results in normal and hirsute women and in mild congenital adrenal hyperplasia.
The variations in plasma cortisol, testosterone and 17-hydroxyprogesterone (17-OHP) induced by an im injection of 0.25 mg… 
1979
1979
Possible genetic linkage disequilibrium between HLA and the 21-hydroxylase deficiency gene (congenital adrenal hyperplasia).
1978
1978
Unusual heterozygotes of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Three otherwise healthy relatives of patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency and salt… 
1977
1977
Increasing fetal adrenal formation of cortisol from pregnenolone during baboon (Papio papio) gestation.
To determine the maturational changes leading to adrenocortical self-sufficiency in baboon neonates, fetal adrenal growth and…