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CYP21A2 gene

Known as: P450C21, CYTOCHROME P450, SUBFAMILY XXI, CYTOCHROME P450, FAMILY 21, SUBFAMILY A, POLYPEPTIDE 2 
This gene plays a role in steroid metabolism.
National Institutes of Health

Related topics

Related topics

17 relations
21-hydroxylase deficiencyAdrenal Cortical HyperplasiaCYP21A2 gene targeted mutation analysis:Prid:Pt:Amnio fld:Nom:MolgenCYP21A2 protein, human

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CYP21A2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
p.H62L, a rare mutation of the CYP21 gene identified in two forms of 21-hydroxylase deficiency.
CONTEXT Steroid 21-hydroxylase deficiency is the most common enzymatic defect causing congenital adrenal hyperplasia with good… 
2007
2007
Reseña de "A Política Brasileira no Século XXI: a prevalência dos programas de transferência de renda" de Maria Ozanira da Silva e SILVA, Maria Carmelita YAZBEK y Geraldo DI GIOVANNI
Highly Cited
2002
Highly Cited
2002
Multiplex minisequencing of the 21-hydroxylase gene as a rapid strategy to confirm congenital adrenal hyperplasia.
BACKGROUND Congenital adrenal hyperplasia (CAH) is a frequent autosomal recessive disease, with a wide range of clinical… 
Highly Cited
1997
Highly Cited
1997
Immunoprecipitation of steroidogenic enzyme autoantigens with autoimmune polyglandular syndrome type I (APS I) sera; further evidence for independent humoral immunity to P450c17 and P450c21
Three steroidogenic P450 cytochromes, steroid 17α‐hydroxylase (P450c17), steroid 21‐hydroxylase (P450c21) and side‐chain cleavage… 
Highly Cited
1997
Highly Cited
1997
Mutation-haplotype analysis of steroid 21-hydroxylase (CYP21) deficiency in Finland. Implications for the population history of defective alleles
Abstract Congenital adrenal hyperplasia (CAH) due to steroid 21-hydroxylase deficiency is a common inherited defect of adrenal… 
Highly Cited
1995
Highly Cited
1995
Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X.
A compact region in the human class III major histocompatibility locus contains the human genes for the fourth component of human… 
Highly Cited
1990
Highly Cited
1990
Gene conversion in steroid 21-hydroxylase genes.
The steroid 21-hydroxylase gene, CYP21B, encodes cytochrome P450c21, which mediates 21-hydroxylation. The gene is located about… 
Highly Cited
1989
Highly Cited
1989
Two distinct areas of unequal crossingover within the steroid 21-hydroxylase genes produce absence of CYP21B.
1989
1989
Major-histocompatibility-complex gene markers and restriction-fragment analysis of steroid 21-hydroxylase (CYP21) and complement C4 genes in classical congenital adrenal hyperplasia patients in a…
The gene CYP21B, encoding the steroid 21-hydroxylase enzyme of adrenal steroid biosynthesis, has been mapped to the human major… 
Highly Cited
1986
Highly Cited
1986
Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression.
Steroid 21-hydroxylase [21-OHase; steroid 21-monooxygenase; steroid, hydrogen-donor:oxygen oxidoreductase (21-hydroxylating); EC… 
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