FAQ

Statistical coupling analysis

Known as: Statistical coupling energy 
Statistical coupling analysis or SCA is a technique used in bioinformatics to measure covariation between pairs of amino acids in a protein multiple… (More)
Wikipedia

Topic mentions per year

Topic mentions per year

2005-2014
0120052014

Related topics

Related topics

5 relations
BioinformaticsMultiple sequence alignmentMutual informationProtein structure prediction
(More)

Related mentions per year

Related mentions per year

1957-2018
1960198020002020
Statistical coupling analysis
Bioinformatics
Mutual information
Sequence alignment
Multiple sequence alignment
Protein structure prediction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Protein Sectors: Statistical Coupling Analysis versus Conservation
Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2015
2015
Hybrid approaches for the detection of networks of critical residues involved in functional motions in protein families
Background Currently there is great interest in identifying critical residues in proteins, to improve our understanding and allow… (More)
Is this relevant?
2014
2014
Capturing coevolutionary signals in repeat proteins Capturing coevolutionary signals in repeat proteins
The analysis of correlations of amino acid occurrences in globular proteins has led to the development of statistical tools that… (More)
Is this relevant?
2012
2012
Note 109: A summary of SCA calculations
This document provides a summary of the current implementation of the statistical coupling analysis (SCA) method. The conceptual… (More)
Is this relevant?
2012
2012
Probing the Mutational Interplay between Primary and Promiscuous Protein Functions: A Computational-Experimental Approach
Protein promiscuity is of considerable interest due its role in adaptive metabolic plasticity, its fundamental connection with… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2011
2011
“Fluctuograms” Reveal the Intermittent Intra-Protein Communication in Subtilisin Carlsberg and Correlate Mechanical Coupling with Co-Evolution
The mechanism of intra-protein communication and allosteric coupling is key to understanding the structure-property relationship… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
An integrated system for studying residue coevolution in proteins
UNLABELLED Residue coevolution has recently emerged as an important concept, especially in the context of protein structures… (More)
  • figure 1
Is this relevant?
2007
2007
Mechanochemical Coupling in the Myosin Motor Domain. II. Analysis of Critical Residues
An important challenge in the analysis of mechanochemical coupling in molecular motors is to identify residues that dictate the… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2006
2006
Structure-Based Identification of Small Molecule Binding Sites Using a Free Energy Model
We separately have shown that the maximal druglike affinity of a given binding site on a protein can be calculated on the basis… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
2005
2005
Inferring interactions from combinatorial protein libraries
Proteins created by combinatorial methods in vitro are an important source of information for understanding sequence-structure… (More)
  • table I
  • table II
Is this relevant?