Stat3 protein

Known as: Acute-Phase Response Factor, Signal Transducer and Activator of Transcription 3, IL6 Response Factor 
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
The Janus kinases (JAKs) and signal transducer and activator of transcription (STAT) proteins, particularly STAT3, are among the… (More)
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Highly Cited
2009
Highly Cited
2009
Colitis-associated cancer (CAC) is the most serious complication of inflammatory bowel disease. Proinflammatory cytokines have… (More)
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Review
2007
Review
2007
Immune cells in the tumour microenvironment not only fail to mount an effective anti-tumour immune response, but also interact… (More)
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Highly Cited
2007
Highly Cited
2007
Interleukin-17 (IL-17)-producing helper T (TH) cells, named as TH(IL-17), TH17, or inflammatory TH (THi), have been recently… (More)
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Highly Cited
2002
Highly Cited
2002
Non-receptor and receptor tyrosine kinases, such as Src and EGF receptor (EGFR), are major inducers of vascular endothelial… (More)
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Highly Cited
1999
Highly Cited
1999
cers are reported to contain constitutively activated STATs are latent transcription factors that mediate STAT proteins, very… (More)
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Highly Cited
1999
Highly Cited
1999
Interleukin 6 (IL-6) is the major survival factor for myeloma tumor cells and induces signaling through the STAT proteins. We… (More)
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Highly Cited
1995
Highly Cited
1995
Cytokines and growth factors induce tyrosine phosphorylation of signal transducers and activators of transcription (STATs) that… (More)
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Highly Cited
1995
Highly Cited
1995
Stat1 and Stat3 are latent transcriptional factors activated initially through phosphorylation on single tyrosine residues… (More)
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Highly Cited
1994
Highly Cited
1994
The STAT family of proteins carries out a dual function: signal transduction and activation of transcription. A new family member… (More)
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