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Spindle Pole Body

Known as: SPB, Body, Spindle Pole, Spindle Pole Bodies 
The spindle pole body (SPB) is the microtubule organizing center (MTOC) in the yeast Saccharomyces that plays a pivotal role in such diverse… Expand
National Institutes of Health

Related topics

Related topics

8 relations

Broader (2)

Cellular StructuresSpindle Poles
MicrobiologicalMitotic Spindle Assembly Checkpoint Protein MAD2APLK1 protein, humanProcess of secretion
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Papers overview

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Highly Cited
2006
Highly Cited
2006
The Sad1-UNC-84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope
The spindle pole body (SPB) is the sole site of microtubule nucleation in Saccharomyces cerevisiae; yet, details of its assembly… Expand
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Highly Cited
2004
Highly Cited
2004
Microtubule Nucleation at Non-Spindle Pole Body Microtubule-Organizing Centers Requires Fission Yeast Centrosomin-Related Protein mod20p
BACKGROUND Many types of differentiated eukaryotic cells display microtubule distributions consistent with nucleation from… Expand
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Highly Cited
2001
Highly Cited
2001
Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex.
Yeast spindle pole bodies (SPBs) duplicate once per cell cycle by a conservative mechanism resulting in a pre-existing 'old' and… Expand
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Highly Cited
1999
Highly Cited
1999
High-voltage electron tomography of spindle pole bodies and early mitotic spindles in the yeast Saccharomyces cerevisiae.
The spindle pole body (SPB) is the major microtubule-organizing center of budding yeast and is the functional equivalent of the… Expand
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Highly Cited
1998
Highly Cited
1998
cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.
The "cut" mutants of Schizosaccharomyces pombe are defective in spindle formation and/or chromosome segregation, but they proceed… Expand
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Highly Cited
1997
Highly Cited
1997
The spindle pole body of Schizosaccharomyces pombe enters and leaves the nuclear envelope as the cell cycle proceeds.
The cycle of spindle pole body (SPB) duplication, differentiation, and segregation in Schizosaccharomyces pombe is different from… Expand
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Highly Cited
1997
Highly Cited
1997
The Yeast Spindle Pole Body Is Assembled around a Central Crystal of Spc42p
The spindle pole body (SPB) is the microtubule organizing center (MTOC) in the yeast Saccharomyces that plays a pivotal role in… Expand
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Highly Cited
1997
Highly Cited
1997
Stu2p: A Microtubule-Binding Protein that Is an Essential Component of the Yeast Spindle Pole Body
Previously we isolated tub2-423, a cold-sensitive allele of the Saccharomyces cerevisiae gene encoding β-tubulin that confers a… Expand
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Highly Cited
1995
Highly Cited
1995
The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability
Spindle formation in fission yeast occurs by the interdigitation of two microtubule arrays extending from duplicated spindle pole… Expand
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Highly Cited
1990
Highly Cited
1990
γ-tubulin is a component of the spindle pole body that is essential for microtubule function in Aspergillus nidulans
We have recently discovered that the mipA gene of A. nidulans encodes gamma-tubulin, a new member of the tubulin superfamily. To… Expand
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