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Spindle Poles

Known as: Pole, Spindle, Poles, Spindle, Spindle Pole 
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Many cancer cells display a CIN (Chromosome Instability) phenotype, by which they exhibit high rates of chromosome loss or gain… Expand
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Review
2007
Review
2007
The gene encoding the Aurora-A protein kinase is located in the 20q13 breast cancer amplicon and is also overexpressed in… Expand
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Review
2005
Review
2005
The three human homologues of Aurora kinases (A, B and C) are essential for proper execution of various mitotic events and are… Expand
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Highly Cited
2004
Highly Cited
2004
For accurate segregation of chromosomes during cell division, microtubule fibres must attach sister kinetochores to opposite… Expand
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Highly Cited
2003
Highly Cited
2003
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle… Expand
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Highly Cited
2002
Highly Cited
2002
How sister kinetochores attach to microtubules from opposite spindle poles during mitosis (bi-orientation) remains poorly… Expand
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Highly Cited
2001
Highly Cited
2001
We discovered that many proteins located in the kinetochore outer domain, but not the inner core, are depleted from kinetochores… Expand
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Highly Cited
2000
Highly Cited
2000
TPX2, the targeting protein for Xenopus kinesin-like protein 2 (Xklp2), was identified as a microtubule-associated protein that… Expand
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Highly Cited
2000
Highly Cited
2000
NuMA is a large nuclear protein whose relocation to the spindle poles is required for bipolar mitotic spindle assembly. We show… Expand
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Highly Cited
1988
Highly Cited
1988
Neuroblast cells in larvae homozygous for mutant alleles of the locus polo show a high frequency of metaphases in which the… Expand
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