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Spindle Poles
Known as:
Pole, Spindle
, Poles, Spindle
, Spindle Pole
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules…
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National Institutes of Health
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Related topics
Related topics
7 relations
Microbiological
Process of secretion
aspects of radiation effects
physiological aspects
Broader (1)
Spindle
Narrower (2)
Spindle Pole Body
polar microtubule
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells
William T. Silkworth
,
Isaac Nardi
,
Lindsey M. Scholl
,
D. Cimini
PLoS ONE
2009
Corpus ID: 14074952
Many cancer cells display a CIN (Chromosome Instability) phenotype, by which they exhibit high rates of chromosome loss or gain…
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Review
2007
Review
2007
Aurora-A: the maker and breaker of spindle poles
A. Barr
,
F. Gergely
Journal of Cell Science
2007
Corpus ID: 23407902
The gene encoding the Aurora-A protein kinase is located in the 20q13 breast cancer amplicon and is also overexpressed in…
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Review
2005
Review
2005
Aurora-A — A guardian of poles
Tomotoshi Marumoto
,
Dongwei Zhang
,
H. Saya
Nature Reviews. Cancer
2005
Corpus ID: 42359141
The three human homologues of Aurora kinases (A, B and C) are essential for proper execution of various mitotic events and are…
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Highly Cited
2003
Highly Cited
2003
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint
Silke Hauf
,
R. Cole
,
+7 authors
J. Peters
Journal of Cell Biology
2003
Corpus ID: 16278410
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle…
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Highly Cited
2002
Highly Cited
2002
Evidence that the Ipl1-Sli15 (Aurora Kinase-INCENP) Complex Promotes Chromosome Bi-orientation by Altering Kinetochore-Spindle Pole Connections
Tomoyuki U. Tanaka
,
N. Rachidi
,
+5 authors
K. Nasmyth
Cell
2002
Corpus ID: 493346
Highly Cited
2001
Highly Cited
2001
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
B. Howell
,
B. McEwen
,
+4 authors
E. Salmon
Journal of Cell Biology
2001
Corpus ID: 16899941
We discovered that many proteins located in the kinetochore outer domain, but not the inner core, are depleted from kinetochores…
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Highly Cited
2001
Highly Cited
2001
Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo
S. Grill
,
P. Gönczy
,
E. Stelzer
,
A. Hyman
Nature
2001
Corpus ID: 4335183
Cell divisions that create daughter cells of different sizes are crucial for the generation of cell diversity during animal…
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Highly Cited
1995
Highly Cited
1995
The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability
I. Hagan
,
M. Yanagida
Journal of Cell Biology
1995
Corpus ID: 1501527
Spindle formation in fission yeast occurs by the interdigitation of two microtubule arrays extending from duplicated spindle pole…
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Review
1992
Review
1992
Mitotic spindle organization by a plus-end-directed microtubule motor
K. Sawin
,
K. Leguellec
,
M. Philippe
,
T. Mitchison
Nature
1992
Corpus ID: 4358461
Intracellular microtubule motor proteins may direct the motile properties and/or morphogenesis of the mitotic spindle (reviewed…
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Highly Cited
1988
Highly Cited
1988
polo, a mitotic mutant of Drosophila displaying abnormal spindle poles.
C. Sunkel
,
D. Glover
Journal of Cell Science
1988
Corpus ID: 19799211
Neuroblast cells in larvae homozygous for mutant alleles of the locus polo show a high frequency of metaphases in which the…
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