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Intrinsic spinal networks, known as central pattern generators (CPGs), control the timing and pattern of the muscle activity… Expand Neural circuits are assembled with remarkable precision during embryonic development, and the selectivity inherent in their… Expand Transplantation approaches using cellular bridges, fetal central nervous system cells, fibroblasts expressing neurotrophin-3 (ref… Expand For many decades, the inability of lesioned central neurons to regrow was accepted almost as a "law of nature", and on the… Expand P.M. Rossini (Chairman) (Rome, Baly), A.T. Barker (Sheffield, UK), A. Berardelli (Rome, Italy), M.D. Caramia (Rome, Italy), G… Expand The guidance of axons to their targets in the developing nervous system is believed to involve diffusible chemotropic factors… Expand There is considerable evidence to implicate N-methyl-D-aspartate (NMDA) receptor activation in the mechanisms that underly… Expand BACKGROUND
Amyotrophic lateral sclerosis (ALS) is a chronic degenerative neurologic disorder characterized by the death of motor… Expand Excitatory amino acids act via receptor subtypes in the mammalian central nervous system (CNS)1–3. The receptor selectively… Expand Acidic amino acids are putative excitatory synaptic transmitters1,2, the ionic mechanism of which is not well understood. Recent… Expand