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Sphingosine 1-Phosphate Receptor 2

Known as: Sphingosine-1-Phosphate Receptor 2, Sphingosine 1-Phosphate Receptor EDG-5, Endothelial Differentiation G-Protein Coupled Receptor 5 
Sphingosine 1-phosphate receptor 2 (353 aa, ~39 kDa) is encoded by the human S1PR2 gene. This protein is involved in transcriptional activation, cell… Expand
National Institutes of Health

Papers overview

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2017
2017
Hepatic encephalopathy (HE) is a neuropsychiatric complication that occurs due to deteriorating hepatic function and this… Expand
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Highly Cited
2015
Highly Cited
2015
UNLABELLED Bile acids are important hormones during the feed/fast cycle, allowing the liver to coordinately regulate nutrient… Expand
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2015
2015
Background: Cyclooxygenase-2 (COX-2) and sphingosine 1-phosphate receptor 2 (S1PR2) are highly expressed in human… Expand
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Highly Cited
2014
Highly Cited
2014
Cholangiocarcinoma (CCA) is an often fatal primary malignancy of the intra- and extrahepatic biliary tract that is commonly… Expand
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Highly Cited
2014
Highly Cited
2014
This study identifies a GPCR, S1PR2, as a receptor for the Nogo-A-Δ20 domain of the membrane protein Nogo-A, which inhibits… Expand
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Highly Cited
2013
Highly Cited
2013
The endothelium, as the interface between blood and all tissues, plays a critical role in inflammation. Sphingosine-1-phosphate… Expand
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2013
2013
Molecular probe tool compounds for the Sphingosine 1-phosphate receptor 2 (S1PR2) are important for investigating the multiple… Expand
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Highly Cited
2012
Highly Cited
2012
Bile acids have been shown to be important regulatory molecules for cells in the liver and gastrointestinal tract. They can… Expand
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2010
2010
Objective—The goals of this study were to identify the signaling pathway by which sphingosine 1-phosphate (S1P) activates RhoA in… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Previous studies have revealed a phosphatase and tensin homolog (PTEN)-dependent interaction between the sphingolipid… Expand
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