FAQ

Sphingosine 1-Phosphate Receptor 2

Known as: Sphingosine-1-Phosphate Receptor 2, Sphingosine 1-Phosphate Receptor EDG-5, Endothelial Differentiation G-Protein Coupled Receptor 5 
Sphingosine 1-phosphate receptor 2 (353 aa, ~39 kDa) is encoded by the human S1PR2 gene. This protein is involved in transcriptional activation, cell… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2017
02420062017

Related topics

Related topics

14 relations
Cytoskeletal ModelingG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIntegral Membrane Proteins
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Sphingosine 1-Phosphate Receptor 2
Plasma membrane
Signal Transduction
Receptors, Cell Surface
G Protein-Coupled Receptor Genes
Receptor Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice
Hepatic encephalopathy (HE) is a neuropsychiatric complication that occurs due to deteriorating hepatic function and this… (More)
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2016
2016
Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis
Sphingosine-1-phosphate receptor 2 (S1PR2) couples with the Gi, Gq, and G12/13 group of proteins, which modulate an array of… (More)
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2016
2016
Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and…
Mast cells (MC) are present in most vascularized tissues around the vasculature likely exerting immunomodulatory functions… (More)
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2016
2016
Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice.
Sphingosine 1-phosphate (S1P) is known to regulate insulin resistance in hepatocytes, skeletal muscle cells, and pancreatic… (More)
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2015
2015
Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line.
Cholangiocarcinoma (CCA) is a rare, but highly malignant primary hepatobiliary cancer with a very poor prognosis and limited… (More)
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2015
2015
FTY720 Phosphate Activates Sphingosine-1-Phosphate Receptor 2 and Selectively Couples to Gα12/13/Rho/ROCK to Induce Myofibroblast Contraction.
FTY720 phosphate (FTY720-P; 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, monodihydrogen phosphate ester) is a nonselective… (More)
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2015
2015
Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice
Sphingosine 1-phosphate (S1P)/S1P receptor (S1PR) system has been implicated in the pathological process of liver injury. This… (More)
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2015
2015
Sphingosine 1-Phosphate Receptor 2 Regulates the Migration, Proliferation, and Differentiation of Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are a multipotent cell population acquired most prominently from bone marrow with the capacity to… (More)
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2014
2014
Sphingosine 1-Phosphate (S1P) Induced Interleukin-8 (IL-8) Release Is Mediated by S1P Receptor 2 and Nuclear Factor κB in BEAS-2B Cells
The airway epithelium may release pro-inflammatory cytokines and chemokines in the asthmatic airway. Sphingosine 1-phosphate (S1P… (More)
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2013
2013
A sphingosine 1-phosphate receptor 2 selective allosteric agonist.
Molecular probe tool compounds for the Sphingosine 1-phosphate receptor 2 (S1PR2) are important for investigating the multiple… (More)
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