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Sphingosine 1-Phosphate Receptor 1

Known as: Antigen CD363, CD363, S1P1 
Sphingosine 1-phosphate receptor 1 (382 aa, ~43 kDa) is encoded by the human S1PR1 gene. This protein plays a role in phospholipid binding.
National Institutes of Health

Related topics

Related topics

19 relations
Cell AdhesionCell MovementCytoskeletal ModelingEndothelial Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
parasite Trypanosoma cruzi
T-cell mediated immune respon ses are crit ical for acqu ired imm unity again st in fect ion by th e in t racellu lar p rotozoan… 
2014
2014
Role of sphingosine 1-phosphate (S1P) and effects of fingolimod, an S1P receptor 1 functional antagonist in lymphocyte circulation and autoimmune diseases
Sphingosine 1-phosphate (S1P), a multi-functional phospholipid mediator, is generated from sphingosine by sphingosine kinases and… 
2014
2014
[Effect of a novel selective S1P1 agonist, Syl948, on mouse skin transplantation].
Syl948 is a synthesized selective S1P1 agonist with novel structure. HTRF-IP1 test indicated that Syl948-P, the active form of… 
2013
2013
Role of Sphingosine 1-Phosphate (S1P) Receptor 1 in Experimental Autoimmune Encephalomyelitis —I
Therapeutic administration of fingolimod hydrochloride (FTY720), the functional antagonist at sphingosine 1-phosphate (S1P… 
2012
2012
S 1 P 1 Receptor Modulation with Cyclical Recovery from Lymphopenia Ameliorates Mouse Model of Multiple Sclerosis
Multiple sclerosis (MS) therapies modulate T-cell autoimmunity in the central nervous system (CNS) but may exacerbate latent… 
2012
2012
Novel piperidinyl monocarboxylic acids as S1P1 receptor agonists
The present invention relates to novel compounds that act as agonists at the S1P (sphingosine-1-phosphate) receptor, compositions… 
2011
2011
Oxadiazole substituted compounds and their use as agonists of S1P1
A compound of formula (I): Formula ** ** or its stereoisomers, N-oxides or salts; wherein: Ring A is phenyl, thiophenyl… 
2009
2009
Sphingosine-1-Phosphate Regulates Glioblastoma Cell Invasiveness through the Urokinase Plasminogen Activator System and CCN 1 / Cyr 61
Glioblastoma multiforme (GBM) is an aggressively invasive brain neoplasm with poor patient prognosis. We have previously shown… 
2009
2009
Thymic egress : S 1 P of 1000
Recent studies have begun to illuminate the mechanism of T-cell export from the thymus, with the identification of a required… 
2005
2005
Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium : regulation of synovial proliferation and inflammatory gene expression
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