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Sphingosine 1-Phosphate Receptor 1

Known as: Antigen CD363, CD363, S1P1 
Sphingosine 1-phosphate receptor 1 (382 aa, ~43 kDa) is encoded by the human S1PR1 gene. This protein plays a role in phospholipid binding.
National Institutes of Health

Related topics

Related topics

19 relations
Cell AdhesionCell MovementCytoskeletal ModelingEndothelial Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Association of Sphingosine‐1‐phosphate (S1P)/S1P Receptor‐1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma
Background Sphingosine‐1‐phosphate (S1P) is a key biolipid signaling molecule that regulates cell growth and survival, but it has… 
2013
2013
Sphingosine 1-Phosphate Receptor 1 (S1P1) Upregulation and Amelioration of Experimental Autoimmune Encephalomyelitis by an S1P1 Antagonist
Sphingosine 1-phosphate receptor 1 (S1P1) is a G protein–coupled receptor that is critical for proper lymphocyte development and… 
2012
2012
Sphingosine 1-Phosphate Receptor 1 as a Useful Target for Treatment of Multiple Sclerosis
Sphingosine 1-phosphate (S1P), a lysophospholipid mediator, is generated from sphingosine by sphingosine kinases and binds five… 
2012
2012
CCR7 with S1P1 signaling through AP-1 for migration of Foxp3+ regulatory T-cells controls autoimmune exocrinopathy.
2009
2009
Involvement of sphingosine-1-phosphate and S1P1 in angiogenesis: analyses using a new S1P1 antagonist of non-sphingosine-1-phosphate analog.
2006
2006
S1P regulation of ovarian carcinoma invasiveness.
Highly Cited
2003
Highly Cited
2003
Sphingosine 1-Phosphate in Amniotic Fluid Modulates Cyclooxygenase-2 Expression in Human Amnion-derived WISH Cells*
The metabolism of arachidonic acid, in particular the generation of prostaglandins (PGs), has been proposed to play a key role in… 
2003
2003
Platelet‐derived growth factor (PDGF)‐induced chemotaxis does not require the G protein‐coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells
Highly Cited
2002
Highly Cited
2002
N‐Glycans of sphingosine 1‐phosphate receptor Edg‐1 regulate ligand‐induced receptor internalization
Endothelial differentiation gene‐1 product (Edg‐1) is a G‐protein‐coupled receptor (GPCR) for the platelet derived bioactive… 
Review
2002
Review
2002
Lysophospholipid Receptors in the Nervous System
The lysophospholipid mediators, lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P), are responsible for cell signaling… 
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