Sphingosine 1-Phosphate Receptor 1

Known as: Antigen CD363, CD363, S1P1 
Sphingosine 1-phosphate receptor 1 (382 aa, ~43 kDa) is encoded by the human S1PR1 gene. This protein plays a role in phospholipid binding.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Sphingosine 1-phosphate (S1P), a lysophospholipid, has gained relevance to multiple sclerosis through the discovery of FTY720… (More)
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Highly Cited
2010
Highly Cited
2010
Sphingolipids are a class of biologically active lipids that have a role in multiple biological processes including inflammation… (More)
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Highly Cited
2010
Highly Cited
2010
This corrects the article DOI: 10.1038/nature07713 
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Highly Cited
2009
Highly Cited
2009
Maintenance of vascular integrity is critical for homeostasis, and temporally and spatially regulated vascular leak is a central… (More)
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Highly Cited
2008
Highly Cited
2008
Although much is known about the migration of T cells from blood to lymph nodes, less is known about the mechanisms regulating… (More)
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Highly Cited
2007
Highly Cited
2007
Sphingosine 1-phosphate (S1P), a multifunctional lipid mediator, regulates lymphocyte trafficking, vascular permeability, and… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Sphingosine 1-phosphate (S1P) is involved in various pathologic conditions and has been implicated as an important… (More)
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Highly Cited
2006
Highly Cited
2006
The mechanisms involved in renal ischemia-reperfusion injury (IRI) are complex and appear to involve the early participation of… (More)
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Highly Cited
2004
Highly Cited
2004
The factors directing marginal zone B cells to the splenic marginal zone are not well understood. Here we report that FTY720, a… (More)
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Highly Cited
2004
Highly Cited
2004
Sphingosine 1-phosphate (S1P) influences heart rate, coronary artery caliber, endothelial integrity, and lymphocyte recirculation… (More)
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