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Spastic Paraplegia

Known as: Spastic Paraplegias, Paraplegia, Spastic, paralysis spinalis spastica 
Spasticity and weakness of the leg and hip muscles. [HPO:probinson]
National Institutes of Health

Related topics

Related topics

27 relations
Allan-Herndon-Dudley syndrome (AHDS)CHOREOATHETOSIS/SPASTICITY, EPISODICEpileptic Encephalopathy, Early Infantile, 4Fitzsimmons-McLachlan-Gilbert syndrome

Broader (1)

Paraplegia

Papers overview

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Highly Cited
2006
Highly Cited
2006
A missense mutation in the coiled-coil domain of the KIF5A gene and late-onset hereditary spastic paraplegia.
BACKGROUND To our knowledge, up to now, only 2 mutations in the KIF5A gene, a member of the kinesin superfamily, have been… 
Highly Cited
2004
Highly Cited
2004
Further evidence of dementia in SPG4-linked autosomal dominant hereditary spastic paraplegia
Objective: To investigate the progression of cognitive impairment and its behavioral aspects in patients with SPG4-linked… 
2004
2004
Spinal implantation of hNT neurons and neuronal precursors: graft survival and functional effects in rats with ischemic spastic paraplegia
Transient spinal ischemia, a complication associated with aortic cross‐clamp may lead to spastic paraplegia. Once fully developed… 
2000
2000
Novel syndromic form of X-linked complicated spastic paraplegia.
This study presents a family with a syndromic form of X-linked mental retardation in which four males in two generations present… 
Highly Cited
1997
Highly Cited
1997
Myelin and lymphocyte protein (MAL/MVP17/VIP17) and plasmolipin are members of an extended gene family.
Highly Cited
1993
Highly Cited
1993
Protection from postischemic spinal cord injury by perfusion cooling of the epidural space.
Review
1992
Review
1992
Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy
SummaryAn epidemiological survey of hereditary ataxias and paraplegias was conducted in Molise, a region of Italy (335, 211… 
Highly Cited
1990
Highly Cited
1990
Hereditary motor and sensory neuropathies and hereditary spastic paraplegia: A magnetic stimulation study
Central motor conduction to the small hand muscles was investigated in 59 patients with peroneal muscular atrophy and hereditary… 
1987
1987
The autosomal dominant form of “pure” familial spastic paraplegia
We studied 33 affected members in a family with autosomal dominant “pure” familial spastic paraplegia (FSP). Symptoms began in… 
Review
1951
Review
1951
HEREDITARY SPASTIC PARAPLEGIA AND HEREDITARY ATAXIA: A Family Demonstrating a Variety of Phenotypic Manifestations
SINCE Seeligmuller1described the clinical, and Strumpell2the pathological, characteristics of hereditary spastic paraplegia, an… 
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