Paraplegia

Known as: extremities lower paralysis, EXTREMITY PARALYSIS, LOWER, Paralysis, Legs 
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with… (More)
National Institutes of Health

Related topics

Related topics

35 relations
AMYLOIDOSIS, HEREDITARY, TRANSTHYRETIN-RELATEDDiplegiaHemiplegiaIn Blood
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Broader (4)

CNS disorderMonoparesisMonoplegianervous system disorder

Narrower (14)

Paraplegia, AtaxicParaplegia, CerebralParaplegia, FlaccidParaplegia, Spinal
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study
BACKGROUND Repeated periods of stimulation of the spinal cord and training increased the ability to control movement in animal… (More)
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Review
2008
Review
2008
Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms
Hereditary spastic paraplegia (HSP) describes a heterogeneous group of genetic neurodegenerative disorders in which the most… (More)
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Highly Cited
2008
Highly Cited
2008
Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial
Olfactory ensheathing cells show promise in preclinical animal models as a cell transplantation therapy for repair of the injured… (More)
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Highly Cited
2004
Highly Cited
2004
The Hereditary Spastic Paraplegia Gene, spastin, Regulates Microtubule Stability to Modulate Synaptic Structure and Function
BACKGROUND Hereditary Spastic Paraplegia (HSP) is a devastating neurological disease causing spastic weakness of the lower… (More)
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Highly Cited
2002
Highly Cited
2002
Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: results of a randomized clinical trial.
OBJECTIVE Despite the use of various strategies for the prevention of spinal cord ischemia, paraplegia and paraparesis continue… (More)
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Highly Cited
2002
Highly Cited
2002
Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics.
Hereditary spastic paraplegia (HSP) is characterized by progressive weakness and spasticity of the lower limbs, caused by the… (More)
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Highly Cited
2002
Highly Cited
2002
Paraplegia after lumbosacral nerve root block: report of three cases.
BACKGROUND CONTEXT Lumbar nerve root blocks and epidural steroid injections are frequently employed in the management of… (More)
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Highly Cited
1999
Highly Cited
1999
Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia
Autosomal dominant hereditary spastic paraplegia (AD-HSP) is a genetically heterogeneous neurodegenerative disorder characterized… (More)
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Highly Cited
1997
Highly Cited
1997
International Standards for Neurological and Functional Classification of Spinal Cord Injury
The ®rst edition of the International Standards for Neurological and Functional Classi®cation of Spinal Cord Injury, ie neural… (More)
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Highly Cited
1969
Highly Cited
1969
The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia
Six hundred and twelve patients with closed spinal injuries are described. The incidence of various types of fracture and… (More)
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