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Sparteine

Known as: Sparteine [Chemical/Ingredient], 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-, Sparteine, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer 
A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
SummarySparteine, an antiarrhythmic and oxytocic drug, is metabolised by N1-oxidation. The sparteine-N1-oxide rearranges with… 
Review
2003
Highly Cited
2003
Review
2003
Review
2003
Of about one dozen human P450 s that catalyze biotransformations of xenobiotics, CYP2D6 is one of the more important ones based… 
Highly Cited
2001
Highly Cited
2001
The oxidation of secondary alcohols is one of the most common and well-studied reactions in chemistry. Although excellent… 
Review
2000
Review
2000
UNLABELLED Tramadol is a synthetic, centrally acting analgesic agent with 2 distinct, synergistic mechanisms of action, acting as… 
Highly Cited
1996
Highly Cited
1996
Highly Cited
1996
Highly Cited
1996
Objective:Codeine O-demethylation to morphine is catalysed by the genetic polymorphic sparteine oxygenase (CYP2D6). The objective…