2-dehydrosparteine

 

Topic mentions per year

Topic mentions per year

1986-1995
012319861995

Papers overview

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1995
1995
We have analysed kinetic parameters of cDNA-derived CYP2D6 proteins derived from the original CYP2D6 cDNA isolate (Gonzalez FJ et… (More)
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1992
1992
Debrisoquine and sparteine are prototype substrates of a genetic deficiency in cytochrome P450-dependent drug metabolism… (More)
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1989
1989
Sparteine oxidation is part of a genetic polymorphism that affects the metabolism of many drugs and is under monogenic control… (More)
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1987
1987
Sparteine metabolism was studied in human liver microsomes from nine extensive ([EM] urinary metabolic ratio [MR] less than 20… (More)
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1986
1986
The formation of the two major metabolites of the antiarrhythmic and oxytocic drug sparteine (2- and 5-dehydrosparteine) exhibits… (More)
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1986
1986
A sensitive method for the assay of sparteine oxidase activity in vitro by microsomal fractions of human liver is described. The… (More)
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1986
1986
  • Kim Brøsen
  • British journal of clinical pharmacology
  • 1986
Sparteine oxidation appeared to be polymorphic in 185 healthy Greenlanders living in Denmark. Six subjects (3.2%) were phenotyped… (More)
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