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Spaglumic Acid

Known as: NAAG 
National Institutes of Health

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1 relation
ISOSPAGLUMIC ACID

Papers overview

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2018
2018
Early detection of elevated lactate levels in a mitochondrial disease model using chemical exchange saturation transfer (CEST) and magnetic resonance spectroscopy (MRS) at 7T-MRI
This study aimed to use chemical exchange saturation transfer (CEST) and magnetic resonance spectroscopy (MRS) at 7T-MRI for… 
2016
2016
Presynaptic, release‐regulating mGlu2‐preferring and mGlu3‐preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease
Presynaptic, release‐regulating metabotropic glutamate 2 and 3 (mGlu2/3) autoreceptors exist in the CNS. They represent suitable… 
2012
2012
Proton MR Spectroscopy–Detectable Major Neurotransmitters of the Brain: Biology and Possible Clinical Applications
SUMMARY: Neurotransmitters are chemical substances that, by definition, allow communication between neurons and permit most… 
2012
2012
mGluR3 and not mGluR2 receptors mediate the efficacy of NAAG peptidase inhibitor in validated model of schizophrenia
2006
2006
Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain – relation to brain concentration
Review
2006
Review
2006
Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy.
GCP II inhibition decreases extracellular excitotoxic glutamate and increases extracellular NAAG, both of which provide… 
Highly Cited
2001
Highly Cited
2001
Expression and acquisition of the conditioned place preference response to cocaine in rats is blocked by selective inhibitors of the enzyme N‐acetylated‐α‐linked‐acidic dipeptidase (NAALADASE)
In this study we examined the effect of 2‐(phosphonomethyl)pentanedioic acid (2‐PMPA) and GPI 5693, selective inhibitors of the… 
1999
1999
Induction of long-lasting depression by (+)-alpha-methyl-4-carboxyphenylglycine and other group II mGlu receptor ligands in the dentate gyrus of the hippocampus in vitro.
1994
1994
A study of polymorphism in the circumsporozoite protein of human malaria parasites.
We have characterized the circumsporozoite (CS) gene sequences of Plasmodium malariae China-1 CDC, isolated recently from a… 
1985
1985
The characterization of the specific binding of [3H]-N- acetylaspartylglutamate to rat brain membranes
[3H]-N-Acetylaspartylglutamate (NAAG) bound saturably and reversibly to crude synaptosomal rat brain membranes. Optimal binding… 
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