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Sp1 Transcription Factor

Known as: Transcription Factor, Sp1, Sp1 Transcription Factor [Chemical/Ingredient], Specificity Protein 1 Transcription Factor 
Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The… 
National Institutes of Health

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Agrin PathwayCYS2-HIS2 Zinc FingersCalcineurin PathwayDNA-Binding Proteins

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2008
2008
A six-nucleotide deletion in the CASP8 promoter is not associated with a susceptibility to breast and prostate cancers in the Polish population
To the editor In a recent study from China, Sun et al. present strong data about a common deletion polymorphism in the CASP8… 
2004
2004
Sp1-targeted inhibition of gene transcription by WP631 in transfected lymphocytes.
The binding of Sp1 transcription factor to DNA is considered a potential target for small ligands designed to interfere with gene… 
2001
2001
The human tuftelin gene: cloning and characterization.
Highly Cited
2000
Highly Cited
2000
Sp1 and C/EBP are necessary to activate the lactoferrin gene promoter during myeloid differentiation.
In this study, we sought to identify factors responsible for the positive modulation of lactoferrin (LF), a neutrophil-specific… 
1999
1999
Nuclear localization of transcription factor Sp1.
Transcription factor Sp1 is importantly related to expression of many cellular genes. In order to identify the nuclear… 
Highly Cited
1996
Highly Cited
1996
Role of zinc-finger proteins Sp1 and zif268/egr-1 in transcriptional regulation of the human synaptobrevin II gene.
Synaptobrevin II is a small integral membrane protein of synaptic vesicles that plays a key role in exocytosis. The 5'-flanking… 
1991
1991
Interaction of Sp1 with the human gamma globin promoter: binding and transactivation of normal and mutant promoters.
We have analyzed the binding of Sp1, a ubiquitously expressed transactivator, to the promoter region of the gamma genes. Low… 
1988
1988
Constraints on spacing between transcription factor binding sites in a simple adenovirus promoter.
The adenovirus 2 E1B transcription unit has an extremely simple promoter consisting of a TATA box and a closely situated GC box… 
1988
1988
Structural organization of the mouse aspartate aminotransferase isoenzyme genes. Introns antedate the divergence of cytosolic and mitochondrial isoenzyme genes.
Highly Cited
1985
Highly Cited
1985
Transcription factor Sp1 recognizes promoter sequences from the monkey genome that are simian virus 40 promoter.
A 440-base-pair fragment of African green monkey genomic DNA shares homology with the transcriptional regulatory region of simian… 
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