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Soft Agar Assay

Soft agar colony formation assay is performed to assay for anchorage independent growth.
National Institutes of Health

Papers overview

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2020
2020
RNA Sequencing Reveals Cancer‐Associated Changes in Laryngeal Cells Exposed to Non‐Acid Pepsin
Laryngopharyngeal reflux (LPR) is a common affliction that contributes to laryngeal inflammation, symptoms that impact quality of… 
2019
2019
XPO1 is a critical player for bortezomib resistance in multiple myeloma: A quantitative proteomic approach.
2015
2015
Subcellular Localization and Ser-137 Phosphorylation Regulate Tumor-suppressive Activity of Profilin-1*
Background: The actin-binding protein profilin-1 is a eukaryotic protein essential for growth, with poorly understood antitumor… 
Highly Cited
2012
Highly Cited
2012
miRNAs expressed differently in cancer stem cells and cancer cells of human gastric cancer cell line MKN‐45
Recent studies show that cancers may originate from special cells named cancer stem cells (CSCs). As miRNAs have a prominent role… 
2007
2007
A High-Throughput Soft Agar Assay for Identification of Anticancer Compound
A 384-well soft agar assay was developed to identify potential novel anticancer compounds. Normally used to detect cell… 
2005
2005
Anti-sense trefoil factor family-3 (intestinal trefoil factor) inhibits cell growth and induces chemosensitivity to adriamycin in human gastric cancer cells.
Highly Cited
2004
Highly Cited
2004
Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo
IntroductionBreast cancer is the leading cause of cancer death in women worldwide. Elevated expression of c-Myc is a frequent… 
Highly Cited
2004
Highly Cited
2004
Lysyl Oxidase Is a Tumor Suppressor Gene Inactivated by Methylation and Loss of Heterozygosity in Human Gastric Cancers
Lysyl oxidase (LOX) and HRAS-like suppressor (HRASLS) are silenced in human gastric cancers and are reported to have growth… 
Highly Cited
2003
Highly Cited
2003
WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer
BackgroundInflammatory breast cancer (IBC) is the most lethal form of locally advanced breast cancer. We found concordant and… 
1981
1981
Cultivation of human melanomas in soft agar. Factors influencing plating efficiency and chemosensitivity
As part of a programme to study the predictive clinical value of a soft agar assay for measuring chemosensitivity of human… 
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