Effect of polyunsaturated fatty acids and antioxidants on lipid peroxidation in tissue cultures.
- V. Gavino, J. Miller, S. O. Ikharebha, G. Milo, D. Cornwell
- BiologyJournal of Lipid Research
- 1 July 1981
Anti-oxidant effects which were time-dependent showed that intracellular MDA was generated from a lipid peroxide precursor during the thiobarbituric acid assay.
The toxicological evaluation of the mycotoxins T-2 and T-2 tetraol using normal human fibroblasts in vitro.
Physiological concentrations of prolactin can promote the growth of human breast tumor cells in culture.
- W. Malarkey, M. Kennedy, L. E. Allred, G. Milo
- Medicine, BiologyJournal of Clinical Endocrinology and Metabolism
- 1 April 1983
There is only indirect evidence at present to suggest a role for PRL in either the genesis or progression of human breast cancer. Here, we report the results of experiments in primary cultures of…
Keratin 19 Downregulation by Oral Squamous Cell Carcinoma Lines Increases Invasive Potential
K19 overexpression in oral SCCs decreases their invasive potential by diminishing migratory capability, and stable expression of the K19 cDNA in K19 negative cell lines altered cell morphology and intercellular adhesiveness, and significantly decreased the number of cells able to migrate through a reconstituted basement membrane.
Effects of steroid hormones in fetal bovine serum on plating and cloning of human cells in vitro
Fetal bovine sera from each of three different commercial sources were tested for their ability to support cloning of human fibroblastoid cells in vitro and addition of estrogen or hydrocortisone to a culture medium that inhibits growth, with subsequent reversal of the inhibitory effect, implies that these hormones competitively regulate growth of responsive cells in vivo.
Transformation of human epithelial cells : molecular and oncogenetic mechanisms
This work presents morphologic and Molecular Characterizations of Plastic Tumor Cell Phenotypes in Culture and Progression from Pigment Cell Patterns to Melanomas in Platyfish-Swordtail Hybrids-Multiple Genetic Changes and a Theme for Tumorsigenesis.
Neoplastic transformation of human epithelial cells in vitro after exposure to chemical carcinogens.
Alatoxin B1, N-methyl-N'-nitro-N-nitrosoguanidine, propanesultone, beta-propiolactone, or ultraviolet absorbance at 254 nm were used successfully as carcinogens.
A comparative study of dimethylhydrazine regioisomers and the methylazoxymethanol metabolite of 1,1- and 1,2-dimethylhydrazine in relation to transformation in human fibroblasts.
Enhanced expression of the 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase gene in human breast tumor cells.