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Small Inducible Cytokine A21

Known as: Chemokine, CCL21, SLC Chemokine, Exodus-2 Chemokine 
A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards DENDRITIC CELLS and T-LYMPHOCYTES.
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
A plexus of lymphatic vessels guides interstitial fluid, passenger leukocytes, and tumor cells toward regional lymph nodes… Expand
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Highly Cited
2001
Highly Cited
2001
Lymphocyte homing to secondary lymphoid tissue is defined by a multistep sequence of interactions between lymphocytes and… Expand
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Highly Cited
2000
Highly Cited
2000
The spontaneous mutant mouse strain, plt/plt, lacks the secondary lymphoid organ chemokine (SLC)-ser gene and has disrupted… Expand
Highly Cited
2000
Highly Cited
2000
Chemokines have been hypothesized to contribute to the selectivity of lymphocyte trafficking not only as chemoattractants, but… Expand
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Highly Cited
1999
Highly Cited
1999
Dendritic cells (DCs) emigrate to regional lymph nodes (LNs) during immune responses via afferent lymphatic channels. Secondary… Expand
Highly Cited
1999
Highly Cited
1999
Migration of antigen-activated CD4 T cells to B cell areas of lymphoid tissues is important for mounting T cell–dependent… Expand
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Highly Cited
1999
Highly Cited
1999
Dendritic cell migration to secondary lymphoid tissues is critical for Ag presentation to T cells necessary to elicit an immune… Expand
Highly Cited
1999
Highly Cited
1999
6Ckine is an unusual chemokine capable of attracting naive T lymphocytes in vitro. It has been recently reported that lack of… Expand
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Highly Cited
1998
Highly Cited
1998
Preferential homing of naive lymphocytes to secondary lymphoid organs is thought to involve the action of chemokines, yet no… Expand
Highly Cited
1997
Highly Cited
1997
By searching the Expressed Sequence Tag (EST) data base, we identified partial cDNA sequences potentially encoding a novel human… Expand
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