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Small Inducible Cytokine A21

Known as: Chemokine, CCL21, SLC Chemokine, Exodus-2 Chemokine 
A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards DENDRITIC CELLS and T-LYMPHOCYTES.
National Institutes of Health

Related topics

Related topics

11 relations
CCL21 geneIn BloodProcess of secretionRecombinant Secondary Lymphoid-Tissue Chemokine

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CCL21 protein, human

Papers overview

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2007
2007
Migratory pathways of gammadelta T cells and response to CXCR3 and CXCR4 ligands: adhesion molecules involved and implications for multiple sclerosis pathogenesis.
Gammadelta T lymphocytes are thought to be involved in multiple sclerosis (MS) pathogenesis. In this work, we discuss the… 
2006
2006
Enhancement of DNA vaccine potency by sandwiching antigen-coding gene between secondary lymphoid tissue chemokine (SLC) and IgG Fc fragment genes
DNA vaccine has become an attractive approach for generating antigen-specific immunity. Targeting antigens to FcRs for IgG (Fc_Rs… 
Highly Cited
2002
Highly Cited
2002
Increased circulating CD11b+CD11c+ dendritic cells (DC) in aged BWF1 mice which can be matured by TNF‐α into BLC/CXCL13‐producing DC
Dendritic cells (DC) play a pivotal role in regulating immune responses. We previously reported aberrant high production of B… 
Review
2002
Review
2002
Chemokines and the immunological synapse
The critical event which initiates an adaptive immune response is the interaction of T cells through the T-cell antigen receptor… 
Highly Cited
2001
Highly Cited
2001
The failure of oral tolerance induction is functionally coupled to the absence of T cells in Peyer's patches under germfree conditions.
Although intestinal bacterial flora has been thought to play a role in the induction of oral tolerance, the mechanism has yet to… 
Highly Cited
2001
Highly Cited
2001
Enhancement of anti‐tumor immunity by tumor cells transfected with the secondary lymphoid tissue chemokine EBI‐1‐ligand chemokine and stromal cell–derived factor‐1αchemokine genes
Several new lymphocyte‐specific chemokines, which attract naive and memory T cells, B cells, dendritic cells and natural killer… 
Highly Cited
2001
Highly Cited
2001
Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
The antitumor efficiency of secondary lymphoid organ chemokine (SLC), a CC chemokine that chemoattracts both dendritic cells (DCs… 
2001
2001
migration Transgenic overexpression of the CC chemokine CCL 21 disrupts T-cell
http://bloodjournal.hematologylibrary.org/content/98/13/3562.full.html Updated information and services can be found at: (4939… 
2001
2001
Cell-dependent Antitumor Immunity Mediated by Secondary Lymphoid Tissue Chemokine : Augmentation of Dendritic Cell-based Immunotherapy 1
Secondary lymphoid tissue chemokine (SLC) is a CC chemokine that is selective in its recruitment of naı̈ve T cells and dendritic… 
Highly Cited
1999
Highly Cited
1999
Distinct migration patterns of naive and effector CD8 T cells in the spleen: correlation with CCR7 receptor expression and chemokine reactivity
Changes in the migration pattern of lymphocytes represent a key event in the evolution of an immune response since they enable… 
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