Sitosterols

Known as: Sitosterols [Chemical/Ingredient], sitosterol 
A family of sterols commonly found in plants and plant oils. Alpha-, beta-, and gamma-isomers have been characterized.
National Institutes of Health

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30 relations

Narrower (22)

24-ethyl-4-cholesten-3-one3-chlorostigmast-5-ene7-dehydrositosterol7-ketositosterol
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Broader (2)

Anticholesteremic AgentsCholestanes
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects
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Papers overview

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Highly Cited
2010
Highly Cited
2010
Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study
BACKGROUND Asclepias curassavica Linn. is a traditional medicinal plant used by tribal people in the western ghats, India, to… (More)
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Highly Cited
2010
Highly Cited
2010
Benign Prostatic Hyperplasia and Male Lower Urinary Tract Symptoms: Epidemiology and Risk Factors
The epidemiology of benign prostatic hyperplasia (BPH) and male lower urinary tract symptoms (LUTS) has evolved considerably… (More)
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Highly Cited
2006
Highly Cited
2006
Plasma sitosterol elevations are associated with an increased incidence of coronary events in men: results of a nested case-control analysis of the Prospective Cardiovascular Münster (PROCAM) study.
BACKGROUND AND AIM Sitosterolemia, a rare genetic disorder characterized by profoundly elevated plasma sitosterol concentrations… (More)
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Highly Cited
2005
Highly Cited
2005
beta-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages.
Uncontrolled production of reactive oxygen species contributes to the pathogenesis of diseases such as cancer and cardiovascular… (More)
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Highly Cited
2004
Highly Cited
2004
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Niemann-Pick C1 Like 1 (NPC1L1) is a protein localized in jejunal enterocytes that is critical for intestinal cholesterol… (More)
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Highly Cited
2002
Highly Cited
2002
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion.
Cholesterol and other sterols exit the body primarily by secretion into bile. In patients with sitosterolemia, mutations in… (More)
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Highly Cited
2002
Highly Cited
2002
Inhibition of intestinal cholesterol absorption by ezetimibe in humans.
BACKGROUND Ezetimibe has been shown to inhibit cholesterol absorption in animal models, but studies on cholesterol absorption in… (More)
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Highly Cited
1996
Highly Cited
1996
beta-Sitosterol and beta-sitosterol glucoside stimulate human peripheral blood lymphocyte proliferation: implications for their use as an immunomodulatory vitamin combination.
The phytosterols, beta-sitosterol (BSS), and its glucoside (BSSG) enhance the in vitro proliferative response of T-cells… (More)
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Highly Cited
1990
Highly Cited
1990
Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population.
To investigate the regulation of serum levels of cholesterol precursor sterols and plant sterols, these noncholesterol sterols… (More)
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Highly Cited
1970
Highly Cited
1970
Metabolism of beta-sitosterol in man.
The metabolism of beta-sitosterol was compared to that of cholesterol in 12 patients. Sterol balance methods were supplemented by… (More)
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