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Silencer Elements, Transcriptional

Known as: Element, Silencer, Transcriptional Silencer Elements, Element, Transcriptional Silencer 
Nucleic acid sequences that are involved in the negative regulation of GENETIC TRANSCRIPTION by chromatin silencing.
National Institutes of Health

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3 relations
aspects of radiation effectsphysiological aspects

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proU silencer

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate
CD4 and the transcription factor ThPOK are essential for the differentiation of major histocompatibility complex class II… 
Highly Cited
2007
Highly Cited
2007
Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease
Huntingtin is a protein that is mutated in Huntington's disease (HD), a dominant inherited neurodegenerative disorder. We… 
Review
2003
Review
2003
Genomic imprinting: intricacies of epigenetic regulation in clusters.
An intriguing characteristic of imprinted genes is that they often cluster in large chromosomal domains, raising the possibility… 
Highly Cited
1998
Highly Cited
1998
Perinuclear localization of chromatin facilitates transcriptional silencing
Transcriptional silencing in Saccharomyces cerevisiae at the HM mating-type loci and telomeres occurs through the formation of a… 
Highly Cited
1998
Highly Cited
1998
Neuronal Expression of Zinc Finger Transcription Factor REST/NRSF/XBR Gene
The identification of a common cis-acting silencer element, a neuron-restrictive silencer element (NRSE), in multiple neuron… 
Highly Cited
1995
Highly Cited
1995
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
Highly Cited
1993
Highly Cited
1993
Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast
Highly Cited
1992
Highly Cited
1992
A common silencer element in the SCG10 and type II Na+ channel genes binds a factor present in nonneuronal cells but not in neuronal cells
Highly Cited
1992
Highly Cited
1992
Silencing the type II sodium channel gene: A model for neural-specific gene regulation
Highly Cited
1983
Highly Cited
1983
Vectors for P element-mediated gene transfer in Drosophila.
We have constructed and tested several new vectors for P element-mediated gene transfer. These vectors contain restriction sites… 
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