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Serpin E2

Known as: Protease Inhibitor 7, Nexin 1, Glia-Derived, Glia-Derived Nexin 1 
A protease nexin and serpin subtype that is specific for several SERINE PROTEASES including UROKINASE; THROMBIN; TRYPSIN; and PLASMINOGEN ACTIVATORS.
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionSERPINE2 geneagonists

Broader (1)

Serine Proteinase Inhibitors

Narrower (1)

Serpine2 protein, rat

Papers overview

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2016
2016
Selective neutralization of the serpin protease nexin‐1 by a specific monoclonal antibody
Protease nexin-1 [PN-1; also termed serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2… 
2011
2011
Na+/H+交換輸送体1(NHE1)とSorting nexin 6(SNX6)の相互作用による安定化
2009
2009
In vitro and In vivo Radiosensitization of Glioblastoma Cells by the Poly ( ADP-Ribose ) Polymerase Inhibitor E 7016
Purpose: Poly (ADP-ribose) polymerase (PARP) inhibitors are undergoing clinical evaluation for cancer therapy. Because PARP… 
2007
2007
Protease nexin I (PNI) in mouse brain is expressed from the same gene as in seminal vesicle
Protease nexin I (PNI), a serine protease inhibitor (serpin), is the most potent tissue inhibitor of thrombin. In the nervous… 
2003
2003
SERPINE 2 ( Protease Nexin I ) Promotes Extracellular Matrix Production and Local Invasion of Pancreatic Tumors in Vivo 1
In large-scale expression profiling analyses, we have previously identified genes differentially expressed between subclones of… 
Highly Cited
1995
Highly Cited
1995
A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death.
Protease nexin I (PNI) is a member of the family of serine protease inhibitors (serpins) that have been shown to promote neurite… 
Review
1994
Review
1994
Proteolytic activity, synapse elimination, and the Hebb synapse.
The Hebb synapse has been postulated to serve as a mechanism subserving both regulation of synaptic strength in the adult nervous… 
1993
1993
The glia‐derived protease nexin 1 persists for over 1 year in rat brain areas selectively lesioned by transient global ischaemia
The re‐expression of the developmentally regulated serine protease inhibitor glia‐derived nexin (GDN) was investigated 1 year… 
1992
1992
Characterization of the heparin-binding site of glia-derived nexin/protease nexin-1.
The interaction of heparin with glia-derived nexin (GDN) has been characterized and compared to that observed between heparin and… 
Highly Cited
1990
Highly Cited
1990
Enzyme specificity of proteinase inhibitor region in amyloid precursor protein of Alzheimer's disease: different properties compared with protease nexin I.
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