FAQ

Serotonin 5-HT4 Receptor Agonists

Known as: Agonist, 5-HT4, 5-HT4 Agonists, 5 HT4 Agonists 
Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT4 RECEPTORS.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
024619912017

Related topics

Related topics

7 relations

Narrower (2)

ATI 7505CJ 033466
In Bloodchemical synthesisisolation & purification analysisphysiological aspects
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Serotonin 5-HT4 Receptor Agonists
physiological aspects
In Blood
chemical synthesis
standards characteristics
ATI 7505

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Drugs acting at 5-HT4 , D2 , motilin, and ghrelin receptors differ markedly in how they affect neuromuscular functions in human isolated stomach.
BACKGROUND Progress in identifying safer, effective drugs to increase gastric emptying is impeded by failed clinical trials. One… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.
BACKGROUND & AIMS Chemotherapy with an anticancer agent generally causes gastrointestinal tract disorders such as vomiting and… (More)
  • figure 1
  • figure 3
  • table 2
Is this relevant?
2007
2007
Does co-administration of a non-selective opiate antagonist enhance acceleration of transit by a 5-HT4 agonist in constipation-predominant irritable bowel syndrome? A randomized controlled trial.
Opioid neurons exhibit tonic restraint on intestinal motility; opioid antagonists stimulate peristalsis and increase transit. In… (More)
Is this relevant?
2006
2006
Desensitization of the peristaltic reflex induced by mucosal stimulation with the selective 5-HT4 agonist tegaserod.
  • John R. Grider
  • American journal of physiology. Gastrointestinal…
  • 2006
The intestinal peristaltic reflex induced by mucosal stimulation is mediated by mucosal release of serotonin (5-HT), which acts… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2005
2005
Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, ameliorates constipation in parkinsonian patients.
Mosapride citrate is a novel selective 5-HT4 receptor agonist. It facilitates acetylcholine release from the enteric cholinergic… (More)
  • figure 1
  • figure 2
Is this relevant?
2002
2002
5-HT4 receptors exert a frequency-related facilitatory control on dorsal raphé nucleus 5-HT neuronal activity.
We investigated, using single-unit recordings in chloral hydrate-anaesthetized rats, the role of serotonin 4 (5-HT4) receptors in… (More)
Is this relevant?
2002
2002
5-HT4 receptors in the hippocampus modulate rat locomotor activity.
In the present study, the ability of 5-hydroxytryptamine-4 (5-HT4) receptors in the hippocampus to enhance locomotor activity in… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine.
BACKGROUND & AIMS The peristaltic reflex induced by mucosal stimuli is mediated by intrinsic sensory calcitonin gene-related… (More)
Is this relevant?
1994
1994
5-HT1A and 5-HT4 receptor colocalization on hippocampal pyramidal cells.
The mixed inhibitory and excitatory effects of 5-HT on hippocampal pyramidal cells were studied on hippocampal slices perfused… (More)
Is this relevant?
1992
1992
5-HT4 receptor activation induces relaxation and associated cAMP generation in rat esophagus.
Changes in mechanical events and intracellular levels of cAMP induced by the activation of the 5-HT4 receptor were investigated… (More)
Is this relevant?