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Serotonin 5-HT4 Receptor Agonists

Known as: Agonist, 5-HT4, 5-HT4 Agonists, 5 HT4 Agonists 
Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT4 RECEPTORS.
National Institutes of Health

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ATI 7505CJ 033466
In Bloodaspects of radiation effectschemical synthesisphysiological aspects

Papers overview

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2015
2015
The 5‐HT4 Agonist Prucalopride Stimulates L‐DOPA‐Induced Dopamine Release in Restricted Brain Regions of the Hemiparkinsonian Rat In Vivo
The efficacy of L-3,4-dihydroxyphenylalanine (L-DOPA) in the treatment of Parkinson’s disease (PD) is impaired by anxiety or… 
Review
2014
Review
2014
Emerging drugs for the treatment of gastroparesis
Introduction: Gastroparesis presents with symptoms of gastric retention with findings of delayed gastric emptying on diagnostic… 
2007
2007
Differences between the abilities of tegaserod and motilin receptor agonists to stimulate gastric motility in vitro
Motilin or 5‐HT4 receptor agonists stimulate gastrointestinal motility. Differences in activity are suggested but direct… 
2007
2007
Does co‐administration of a non‐selective opiate antagonist enhance acceleration of transit by a 5‐HT4 agonist in constipation‐predominant irritable bowel syndrome? A randomized controlled trial
Abstract  Opioid neurons exhibit tonic restraint on intestinal motility; opioid antagonists stimulate peristalsis and increase… 
2004
2004
Effects of tegaserod on Fos, substance P and calcitonin gene-related peptide expression induced by colon inflammation in lumbarsacral spinal cord.
AIM To investigate the mechanisms of tegaserod, a partial 5-HT4 agonist, in reducing visceral sensitivity by observing Fos… 
2004
2004
Serotonin‐induced potentiation of cholinergic responses to electrical field stimulation in normal and neurogenic overactive human detrusor muscle
The smooth muscle cells of the urinary tract are again the subject of much study, as is reflected by the papers in this section… 
2002
2002
5‐HT4 receptors in the hippocampus modulate rat locomotor activity
In the present study, the ability of 5‐hydroxytryptamine‐4 (5‐HT4) receptors in the hippocampus to enhance locomotor activity in… 
2002
2002
Tegaserod: A 5-HT4 agonist for women with constipation-predominant irritable bowel syndrome
Tegaserod maleate (Zelnorm), an aminoguanidine indole is the first selectve partial 5-HT 4 agonist approved by FDA for the short… 
Review
2000
Review
2000
Why the enteric nervous system is important to clinicians
The enteric nervous system (ENS) is central to normal gut function and is involved in most, if not all, disorders of the luminal… 
1998
1998
Investigation into the effect of 5-hydroxytryptamine on fluid transport in the rat small intestine.
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