Seroquel

Known as: seroquel [brand name] 
brand name of quetiapine, a drug used to treat schizophrenia and bipolar disorder
National Institutes of Health

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1999
1999
The goal of antipsychotic drug development efforts over the past 10 years has been to develop agents with increased efficacy and… (More)
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1998
Highly Cited
1998
BACKGROUND Prepulse inhibition (PPI) of startle provides an operational measure of sensorimotor gating in which a weak stimulus… (More)
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1998
Highly Cited
1998
Sensorimotor gating of the startle reflex – measured by prepulse inhibition (PPI) – is impaired in schizophrenia patients and in… (More)
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Highly Cited
1997
Highly Cited
1997
Five fixed doses of the atypical antipsychotic "Seroquel" (quetiapine) were evaluated to delineate a dose-response relationship… (More)
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1997
Highly Cited
1997
BACKGROUND Quetiapine fumarate (Seroquel [ICI 204,636]) is an atypical dibenzothiazepine antipsychotic with a greater affinity… (More)
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1996
Highly Cited
1996
Phencylidine (PCP) is a psychotomimetic noncompetitive glutamate antagonist that has been used in studies of the neural… (More)
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1996
Highly Cited
1996
Risperidone and its active metabolite 9-OH-risperidone were compared to reference antipsychotic drugs (haloperidol, pipamperone… (More)
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1996
Highly Cited
1996
The affinities of olanzapine, clozapine, haloperidol, and four potential antipsychotics were compared on binding to the neuronal… (More)
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1993
Highly Cited
1993
Seroquel and the atypical antipsychotic clozapine were compared using a number of biochemical measures in rats which are… (More)
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1993
1993
Extracellular single unit recording techniques were employed to compare the effects of seroquel with the reference antipsychotic… (More)
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