ICI 204,636

Known as: 204636, ICI, 204,636, ICI, ICI-204636 
 
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
Histone deacetylase (HDAC) 6 is a subtype of the HDAC family; it deacetylates α-tubulin and increases cell motility. Here, we… (More)
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2003
2003
Leydig cells, which produce the primary male steroid hormone testosterone (T), express the two estrogen receptor (ER) subtypes… (More)
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2000
2000
BACKGROUND Quetiapine (ICI 204,636, 'Seroquel') is a new atypical antipsychotic agent with a similar binding profile to the… (More)
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Highly Cited
1996
Highly Cited
1996
ICI 204,636 is a new, potentially atypical antipsychotic. In early phase II trials, the antipsychotic was well tolerated and… (More)
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1996
1996
Treatment with standard antipsychotic medications causes side effects such as hyperprolactinemia and extrapyramidal symptoms… (More)
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Highly Cited
1996
Highly Cited
1996
Phencylidine (PCP) is a psychotomimetic noncompetitive glutamate antagonist that has been used in studies of the neural… (More)
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1995
1995
We evaluated the effects of ICI 204,636 in 12 hospitalized patients with schizophrenia in a double-blind, placebo-controlled… (More)
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1994
1994
Seroquel (ICI 204,636) is a mixed D2/5HT2 antagonist with a preclinical profile suggestive of potential antipsychotic efficacy… (More)
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Highly Cited
1992
Highly Cited
1992
The ability of estrogens to stimulate the transcriptional activity of the estrogen receptor can be inhibited by a diverse range… (More)
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Highly Cited
1991
Highly Cited
1991
N-(5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N- methylamino]-2-thenoyl)-L-glutamic acid (ICI D1694) is a water… (More)
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