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Serine/Threonine Kinase Inhibitor

Any substance that inhibits serine/threonine protein kinase, an enzyme that phosphorylates the hydroxyl group of serine or threonine on various… 
National Institutes of Health

Papers overview

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2010
2010
Preliminary results of a phase II study of rituximab (R), gemcitabine (Gem), oxaliplatin (Ox) plus enzastaurin (ENZ) followed by ENZ maintenance as salvage regimen for patients with relapsed or…
8069 Background: PKC overexpression is observed in relapsed/refractory DLBCL. Enzastaurin (ENZ), an oral serine/threonine kinase… 
2008
2008
Phase I/II study of enzastaurin (ENZ) plus temozolomide (TMZ) and radiation therapy (XRT) in patients with glioblastoma multiforme (GBM) or gliosarcoma (GS)
3559 Background: ENZ, an oral serine/threonine kinase inhibitor, suppresses signaling through PKCβ and the PI3K/AKT pathways to… 
Review
2007
Review
2007
Enzastaurin , a Protein Kinase C B ^ Selective Inhibitor , and Its PotentialApplicationasanAnticancer AgentinLungCancer
Enzastaurin, an oral serine/threonine kinase inhibitor, suppresses signaling throughprotein kinase C (PKC)-h and the… 
2002
2002
Inhibition of human immunodeficiency virus type 1 replication by a bioavailable serine/threonine kinase inhibitor, fasudil hydrochloride
2000
2000
Signal Mediators for Phytoalexin Production in Defense Response of Oats Elicited by Victorin as a Specific Elicitor
Signals mediating phytoalexin (PA) production were analyzed in primary leaves of oats cv. Iowa X469 treated with an elicitor… 
1993
1993
Cells to Apoptosis Induced by Various Antitumor Agents The Cell Cycle Related Differences in Susceptibility of HL-60 Updated
The studies were aimed to detect the cell cycle-associated differences in the susceptibility of HL-60 cells to apoptosis induced…