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Semaphorins

Known as: Semaphorin, Semaphorins [Chemical/Ingredient] 
A family of proteins that mediate AXONAL GUIDANCE. Semaphorins act as repulsive cues for neuronal GROWTH CONES and bind to receptors on their… Expand
National Institutes of Health

Papers overview

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Review
2006
Review
2006
Damage to the adult CNS often leads to persistent deficits due to the inability of mature axons to regenerate after injury… Expand
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Review
2005
Review
2005
Semaphorins are secreted or transmembrane proteins that regulate cell motility and attachment in axon guidance, vascular growth… Expand
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Highly Cited
2003
Highly Cited
2003
The motility and morphogenesis of endothelial cells is controlled by spatio-temporally regulated activation of integrin adhesion… Expand
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Highly Cited
2003
Highly Cited
2003
Neuropilin-1 (Npn-1) is a receptor that binds multiple ligands from structurally distinct families, including secreted… Expand
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Review
2002
Review
2002
Malignant disease occurs when neoplastic cells abandon their primary site of accretion, cross tissue boundaries and penetrate the… Expand
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Highly Cited
1999
Highly Cited
1999
In Drosophila, plexin A is a functional receptor for semaphorin-1a. Here we show that the human plexin gene family comprises at… Expand
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Highly Cited
1999
Highly Cited
1999
Class 1 and 3 semaphorins repulse axons but bind to different cell surface proteins. We find that the two known semaphorin… Expand
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Highly Cited
1997
Highly Cited
1997
The semaphorin family contains a large number of phylogenetically conserved proteins and includes several members that have been… Expand
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Highly Cited
1997
Highly Cited
1997
Extending axons in the developing nervous system are guided to their targets through the coordinate actions of attractive and… Expand
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Highly Cited
1993
Highly Cited
1993
In addition to its expression on subsets of axons, grasshopper Semaphorin I (Sema I, previously called Fasciclin [Fas] IV) is… Expand
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