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Selegiline, (R,S)-Isomer

Known as: Deprenalin, Deprenil 
National Institutes of Health

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Related topics

3 relations
DeprenylSelegilineTilorone Hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
The potentiation of the anti akinetic effect after L-Dopa treatment by an inhibitor of Mao-B, deprenil
The potentiation of the ami akinetic effect after L-Dopa treatment by an inhibitor of monoamine oxidase (MAO) “B”, Deprenil, has… 
Highly Cited
1986
Highly Cited
1986
1-Methyl-4-phenylpyridinium (MPP+) but not 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) selectively destroys dopaminergic neurons in cultures of dissociated rat mesencephalic neurons
Highly Cited
1985
Highly Cited
1985
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: relationships between monoamine oxidase, MPTP metabolism and neurotoxicity.
Highly Cited
1984
Highly Cited
1984
Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors
1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) causes degeneration of the dopaminergic nigrostriatal pathway in several… 
Highly Cited
1977
Highly Cited
1977
Dopamine is a monoamine oxidase B substrate in man
DURING the past decade, the central neurotransmitter, dopamine (DA), has been much studied for it is known to be involved in… 
Highly Cited
1977
Highly Cited
1977
IMPLICATIONS OF COMBINED TREATMENT WITH 'MADOPAR' AND L-DEPRENIL IN PARKINSON'S DISEASE A Long-term Study
Highly Cited
1977
Highly Cited
1977
EVIDENCE FOR DOPAMINE DEAMINATION BY BOTH TYPE A AND TYPE B MONOAMINE OXIDASE IN RAT BRAIN in vivo AND FOR THE DEGREE OF INHIBITION OF ENZYME NECESSARY FOR INCREASED FUNCTIONAL ACTIVITY OF DOPAMINE…
1 Tranylcypromine (20 mg/kg) administration to rats totally inhibited brain monoamine oxidase (MAO) oxidation of 5… 
Highly Cited
1977
Highly Cited
1977
Properties of monoamine oxidase (MAO) in human blood platelets, plasma, lymphocytes and granulocytes.
  • P. BondR. Cundall
  • Clinica chimica acta; international journal of…
  • 1977
  • Corpus ID: 24562170
Highly Cited
1976
Highly Cited
1976
Quipazine: Its effects on rat brain 5-hydroxytryptamine metabolism, monoamine oxidase activity and behaviour
Highly Cited
1975
Highly Cited
1975
EFFECTS OF MONOAMINE OXIDASE INHIBITION BY CLORGYLINE, DEPRENIL OR TRANYLCYPROMINE ON 5‐HYDROXYTRYPTAMINE CONCENTRATIONS IN RAT BRAIN AND HYPERACTIVITY FOLLOWING SUBSEQUENT TRYPTOPHAN ADMINISTRATION
1 The effect of various doses of tranylcypromine on the degree of inhibition of rat brain monoamine oxidase (MAO) using 5… 
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