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Selective Serotonin Reuptake Inhibitors

Known as: SSRI, SSRIs, Selective Serotonin Reuptake Inhibitor 
Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Serotonin Reuptake Inhibitor [EPC]response to fluoxetine

Broader (1)

Serotonin Uptake Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Current Status of Animal Models of Posttraumatic Stress Disorder: Behavioral and Biological Phenotypes, and Future Challenges in Improving Translation
Increasing predictability of animal models of posttraumatic stress disorder (PTSD) has required active collaboration between… Expand
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Review
2016
Review
2016
Systematic Review and Meta-Analysis: Dose-Response Relationship of Selective Serotonin Reuptake Inhibitors in Major Depressive Disorder.
OBJECTIVE Previous studies suggested that the treatment response to selective serotonin reuptake inhibitors (SSRIs) in major… Expand
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Highly Cited
2009
Highly Cited
2009
Emotional side-effects of selective serotonin reuptake inhibitors: qualitative study.
BACKGROUND Some people who take selective serotonin reuptake inhibitor (SSRI) antidepressants report that their experience of… Expand
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Review
2008
Review
2008
Interaction between BDNF and Serotonin: Role in Mood Disorders
Brain-derived neurotrophic factor (BDNF) and serotonin (5-hydroxytryptamine, 5-HT) are two seemingly distinct signaling systems… Expand
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Highly Cited
2007
Highly Cited
2007
Effect of selective serotonin reuptake inhibitors on the risk of fracture.
BACKGROUND Depression and osteoporotic fractures are common ailments among elderly persons. Selective serotonin reuptake… Expand
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Highly Cited
2002
Highly Cited
2002
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.
OBJECTIVE Studies have demonstrated low concentrations of gamma-aminobutyric acid (GABA) in the plasma and CSF of individuals… Expand
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Highly Cited
2001
Highly Cited
2001
Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors.
BACKGROUND It had been suggested that the antidepressant venlafaxine, which inhibits reuptake of both serotonin and (at higher… Expand
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Highly Cited
2000
Highly Cited
2000
Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability.
BACKGROUND A meta-analysis of the efficacy and tolerability of selective serotonin reuptake inhibitors (SSRIs) against tricyclic… Expand
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Highly Cited
1999
Highly Cited
1999
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes.
The neurosteroid 3alpha-hydroxysteroid-5alpha-pregnan-20-one (allopregnanolone) acts as a positive allosteric modulator of gamma… Expand
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Highly Cited
1998
Highly Cited
1998
Selective serotonin reuptake inhibitor discontinuation syndrome: a randomized clinical trial
BACKGROUND Recent reports describe discontinuation-emergent adverse events upon cessation of selective serotonin reuptake… Expand
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