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Selective Serotonin Reuptake Inhibitors

Known as: SSRI, SSRIs, Selective Serotonin Reuptake Inhibitor 
Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell… 
National Institutes of Health

Related topics

Related topics

3 relations
Serotonin Reuptake Inhibitor [EPC]response to fluoxetine

Broader (1)

Serotonin Uptake Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Effect of selective serotonin reuptake inhibitors on the risk of fracture.
BACKGROUND Depression and osteoporotic fractures are common ailments among elderly persons. Selective serotonin reuptake… 
Review
2004
Review
2004
Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data
Review
2003
Review
2003
The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review.
Highly Cited
2002
Highly Cited
2002
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.
OBJECTIVE Studies have demonstrated low concentrations of gamma-aminobutyric acid (GABA) in the plasma and CSF of individuals… 
Highly Cited
2001
Highly Cited
2001
Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors
Background It had been suggested that the antidepressant venlafaxine, which inhibits reuptake of both serotonin and (at higher… 
Highly Cited
2000
Highly Cited
2000
Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability.
  • I. Anderson
  • Journal of Affective Disorders
  • 2000
  • Corpus ID: 32353165
Review
1999
Review
1999
Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study
Abstract Objective: To examine the association between selective serotonin reuptake inhibitors and risk of upper gastrointestinal… 
Highly Cited
1999
Highly Cited
1999
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes.
The neurosteroid 3alpha-hydroxysteroid-5alpha-pregnan-20-one (allopregnanolone) acts as a positive allosteric modulator of gamma… 
Review
1997
Review
1997
Clinically Relevant Pharmacology of Selective Serotonin Reuptake Inhibitors
  • S. Preskorn
  • Clinical Pharmacokinetics
  • 1997
  • Corpus ID: 43164418
SummaryThis paper presents an overview of the clinically relevant pharmacology of selective serotonin reuptake inhibitors (SSRIs… 
Review
1994
Review
1994
Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)
  • J. Hyttel
  • International Clinical Psychopharmacology
  • 1994
  • Corpus ID: 30166780
Established antidepressants including tricyclic antidepressants (TCAs), tetracyclic antidepressants and monoamine oxidase… 
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