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Safrole

Known as: Safroles, Allylcatechol Methylene Ether, 1,3-Benzodioxole, 5-(2-propenyl)- 
A naturally-occurring, colorless to slightly yellow liquid that is soluble in ethanol, ether, and chloroform. Safrole is no longer used in the United… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Anew series of antinociceptive compounds belonging to the N-acylarylhydrazone (NAH) class were synthesized from natural safrole… Expand
Review
1998
Review
1998
ABSTRACT: Melatonin, the chief secretory product of the pineal gland, is a direct free radical scavenger and indirect antioxidant… Expand
Review
1995
Review
1995
Abstract: This survey summarizes the findings, accumulated within the last 2 years, concerning melatonin's role in defending… Expand
Highly Cited
1994
Highly Cited
1994
Hepatic DNA adduct formation induced by the chemical carcinogen, safrole, was suppressed by both endogenous pineal melatonin… Expand
Highly Cited
1993
Highly Cited
1993
Melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in a dose-dependent manner. Total DNA-adduct… Expand
Highly Cited
1990
Highly Cited
1990
  • B. Ames, L. Gold
  • Proceedings of the National Academy of Sciences…
  • 1990
  • Corpus ID: 953338
The administration of chemicals at the maximum tolerated dose (MTD) in standard animal cancer tests is postulated to increase… Expand
  • figure 1
Highly Cited
1987
Highly Cited
1987
Further information on the structure-activity relationships among the synthetic and naturally occurring alkenylbenzene… Expand
Highly Cited
1986
Highly Cited
1986
Exceedingly sensitive procedures are required to detect the presence of covalent DNA adducts in humans exposed to environmental… Expand
Highly Cited
1984
Highly Cited
1984
When a series of nine alkenylbenzenes were administered to preweanling male mice, safrole, estragole and methyleugenol induced a… Expand
Highly Cited
1983
Highly Cited
1983
Twenty-three naturally occurring and synthetic alkenylbenzene derivatives structurally related to the hepatocarcinogen safrole (1… Expand