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1,3-benzodioxole

Known as: 1,2-(methylenedioxy)benzene, methylene dioxybenzene, 1,3-dioxaindane 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2017
0519672017

Related topics

Related topics

2 relations

Broader (1)

Benzodioxoles
Safrole

Related mentions per year

Related mentions per year

1960-2018
1960198020002020
1,3-benzodioxole
Safrole
Benzodioxoles

Papers overview

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2011
2011
Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties.
We described herein the discovery of 1-(2-(benzo[d] [1,3]dioxol-6-yl)ethyl)-4-(2-methoxyphenyl) piperazine (LASSBio-772), as a… (More)
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2011
2011
Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.
A new series of tacrine-multialkoxybenzene hybrids (9a-9n) were designed, synthesized and evaluated as dual inhibitors of… (More)
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2007
2007
Synthesis and antitumour evaluation of peptidyl-like derivatives containing the 1,3-benzodioxole system.
In the scope of a research program aiming at the synthesis and pharmacological evaluation of novel possible antitumour prototype… (More)
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2007
2007
Discovery and investigation of antiproliferative and apoptosis-inducing properties of new heterocyclic podophyllotoxin analogues accessible by a one-step multicomponent synthesis.
Podophyllotoxin has been extensively used as a lead agent in the development of new anticancer drugs. On the basis of the… (More)
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2004
2004
Synthesis, antitumour and antimicrobial activities of new peptidyl derivatives containing the 1,3-benzodioxole system.
Two series of 5 and 6-substituted 1,3-benzodioxole peptidyl derivatives were synthesized and evaluated as antitumour and… (More)
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2003
2003
Synthesis and cytotoxic activity of 1,3-benzodioxole derivatives. Note II.
A series of 1,3-benzodioxoles (2-12) were synthesized and evaluated for their in vitro ability to inhibit the growth of three… (More)
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2002
2002
Synthesis and antitumor activity of 1,3-benzodioxole derivatives.
A series of 1,3-benzodioxoles (5-19) was synthesized and evaluated for their in vitro antitumor activity against human tumor cell… (More)
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1991
1991
Metabolism of methylenedioxyphenyl compounds by rabbit liver preparations. Participation of different cytochrome P450 isozymes in the demethylenation reaction.
The cytochrome P450-mediated oxidative demethylenation of the benzo-1,3-dioxoles (methylenedioxyphenyl compounds, MDPs… (More)
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1985
1985
Induction of rat-hepatic microsomal cytochrome P-450 and aryl hydrocarbon hydroxylase by 1,3-benzodioxole derivatives.
Several 1,3-benzodioxoles (BD) and related compounds were studied in relation to their ability to generate metabolite complexes… (More)
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1972
1972
[Derivatives of methylenedioxybenzene. 35. A novel synthesis of 3,6 dihydroxy-2-ethyl-1,4-benzoquinone, embelin, vilangin, rapanone, dihydromaesaquinone, bhogatin, spinulosin and oosporein].
 
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