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1,3-benzodioxole

Known as: 1,2-(methylenedioxy)benzene, methylene dioxybenzene, 1,3-dioxaindane 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

BenzodioxolesDioxolesoxygenous heterocyclic compound
Safrole

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.
A new series of tacrine-multialkoxybenzene hybrids (9a-9n) were designed, synthesized and evaluated as dual inhibitors of… Expand
Highly Cited
2007
Highly Cited
2007
Discovery and investigation of antiproliferative and apoptosis-inducing properties of new heterocyclic podophyllotoxin analogues accessible by a one-step multicomponent synthesis.
Podophyllotoxin has been extensively used as a lead agent in the development of new anticancer drugs. On the basis of the… Expand
2007
2007
Synthesis and antitumour evaluation of peptidyl-like derivatives containing the 1,3-benzodioxole system.
In the scope of a research program aiming at the synthesis and pharmacological evaluation of novel possible antitumour prototype… Expand
Highly Cited
2006
Highly Cited
2006
Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules.
Significant progress has been made in the direct arylation of simple arenes. A number of catalyst systems have been developed… Expand
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Highly Cited
2004
Highly Cited
2004
Synthesis, antitumour and antimicrobial activities of new peptidyl derivatives containing the 1,3-benzodioxole system.
Two series of 5 and 6-substituted 1,3-benzodioxole peptidyl derivatives were synthesized and evaluated as antitumour and… Expand
Highly Cited
1991
Highly Cited
1991
Cytochrome P450 metabolic intermediate complexes from macrolide antibiotics and related compounds.
  • M. Franklin
  • Methods in enzymology
  • 1991
    • Corpus ID: 45694069
Publisher Summary This chapter discusses the cytochrome P450 metabolic intermediate (MI) complexes from macrolide antibiotics and… Expand
Highly Cited
1976
Highly Cited
1976
Inhibition of mouse testicular DNA synthesis by mutagens and carcinogens as a potential sample mammalian assay for mutagenesis.
Since mutagenic substances induce structural changes in DNA, studies were undertaken to determine whether substances would modify… Expand
Highly Cited
1967
Highly Cited
1967
The relationship between microsomal epoxidation and lipid peroxidation in houseflies and pig liver and the inhibitory effect of derivatives of 1,3-benzodiozole (methylenedioxybenzene).
Abstract The epoxidation of aldrin by microsomal preparations from houseflies and pig liver was markedly inhibited by a number of… Expand
Highly Cited
1965
Highly Cited
1965
TOXIC PROPERTIES OF COMPOUNDS RELATED TO SAFROLE.
Abstract Dihydrosafrole on chronic feeding produced benign and malignant esophageal tumors. Safrole is a hepatic carcinogen… Expand
Highly Cited
1964
Highly Cited
1964
A COMPARISON OF THE TOXICITY OF SOME ALLYL, PROPENYL, AND PROPYL COMPOUNDS IN THE RAT.
Summary The toxicity in the rat of a number of allyl, propenyl, propyl, and related compounds has been compared using as criteria… Expand
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