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Benzodioxoles

Known as: Methylenedioxybenzenes, 1,3 Dioxaindans, 1,3 Dioxindans 
Compounds based on benzene fused to oxole. They can be formed from methylated CATECHOLS such as EUGENOL.
National Institutes of Health

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1,3-benzodioxole2,6-didehydropeperomin B2-hydroxy-4,5-methylenedioxypropiophenone2-hydroxypropylnortadalafil
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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2017
2017
Antimalarial and cytotoxic activities of roots and fruits fractions of Astrodaucus persicus extract
Objective(s): Astrodaucus persicus (Apiaceae) is one of the two species of this genus which grows in different parts of Iran… 
2014
2014
Metabolism-oriented Lead Optimization of Propargyl-linked DHFR Inhibitors
2009
2009
QSAR of antilipid peroxidative activity of substituted benzodioxoles using chemometric tools
Search and development of new effective antioxidant molecules with improved activity is of both biological and commercial… 
2004
2004
Thermodynamic study of sesamol, piperonyl alcohol, piperonylic acid and homopiperonylic acid: a combined experimental and theoretical investigation.
The standard (p(o)= 0.1 MPa) molar energies of combustion in oxygen, at T= 298.15 K, of four 1,3-benzodioxole derivatives… 
2001
2001
In vitro prediction of carcinogenicity using a bovine papillomavirus DNA–carrying C3H/10T½ cell line (T1). II: Results from the testing of 100 chemicals
A new in vitro test for identifying carcinogens is evaluated against a testing database of 100 chemicals including the following… 
1999
1999
Total synthesis of a natural antioxidant and structure-activity relationships of related compounds.
A total synthesis of benzodioxole derivative 1 was achieved via a palladium(0)-catalyzed cross-coupling reaction in a 68% overall… 
1998
1998
Differential induction of cytochrome P450 gene expression by 4n‐alkyl‐methylenedioxybenzenes in primary rat hepatocyte cultures
A well‐characterized primary rat hepatocyte culture system was used to examine induction patterns of cytochrome 450 gene… 
1997
1997
The prevention of ferric nitrilotriacetate-induced nephro- and hepatotoxicity by methylenedioxybenzene antioxidants.
1990
1990
Selective expression of cytochrome P450 isozymes by 4-n-alkyl-methylenedioxybenzenes in rat lung cells.
1984
1984
Induction and suppression of N-nitrosomethylbenzylamine activation by microsomes from rat liver and esophagus.
Male Sprague-Dawley rats were pretreated with various chemicals to determine their effects on the microsomal activation of the… 
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