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2-hydroxy-4,5-methylenedioxypropiophenone

Known as: kakuol 
National Institutes of Health

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2 relations

Broader (2)

BenzodioxolesPropiophenones

Papers overview

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2020
2020
Design, synthesis and antifungal activity of amide and imine derivatives containing a kakuol moiety.
2020
2020
[Identification based on HPLC and anti-inflammatory targets as well as related constituents analysis of Asarum heterotropoides var. mandshuricum and A. sieboldii].
The present work is to establish an HPLC characteristic chromatograms of Asarum heterotropoides var. mandshuricum(AH) and A… 
2014
2014
Natural products as sources of new fungicides (I): synthesis and antifungal activity of Kakuol derivatives against phytopathogenic fungi
In order to establish an advanced structural-activity relationship (SAR) and to explore the feasibility of kakuol analogues with… 
2014
2014
Simultaneous Determination of Twenty-Two Components in Asari Radix et Rhizoma by Ultra Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry
Abstract Asari Radix et Rhizoma is a herbal medicine for the treatment of common cold, rhinitis, etc. An ultra performance liquid… 
2013
2013
A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction.
2010
2010
Synthesis and Antifungal Activity of 2‐Hydroxy‐4,5‐methylenedioxyaryl Ketones as Analogues of Kakuol
In a study aiming to determine the structural elements essential to the antifungal activity of kakuol, we synthesized a series of… 
2008
2008
Constituents of Asarum sieboldii with Inhibitory Activity on Lipopolysaccharide (LPS)‐Induced NO Production in BV‐2 Microglial Cells
Bioassay‐guided fractionation of the root extract of Asarum sieboldii led to the isolation of the four active compounds… 
2008
2008
A new natural product and insecticidal amides from seeds of Piper nigrum Linn.
Studies on the petroleum ether soluble and insoluble fraction of ethanol extract of dried ground seeds of Piper nigrum resulted… 
2007
2007
Isolation of Melanin Biosynthesis Inhibitory Compounds from the Roots of Asarum sieboldii
− Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car3-ene-2,5-dione… 
2005
2005
Isolation and antifungal activity of kakuol, a propiophenone derivative from Asarum sieboldii rhizome.
An antifungal substance active against Colletotrichum orbiculare (Berk & Mont) Arx was isolated from the methanol extracts of… 
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