Skip to search formSkip to main contentSkip to account menu

STAT6 protein, human

Known as: signal transducer and activator of transcription 6 protein, human, Transcription Factor IL-4 STAT, Signal Transducer and Activator of Transcription 6 
Signal transducer and activator of transcription 6 (847 aa, ~94 kDa) is encoded by the human STAT6 gene. This protein is involved in the modulation… 
National Institutes of Health

Related topics

Related topics

14 relations
DNA-Binding ProteinsGenes, RegulatorIL4 Signaling PathwaySH2 Domain

Broader (1)

STAT6 Transcription Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Astrocytes, but Not Microglia, Rapidly Sense H2O2 via STAT6 Phosphorylation, Resulting in Cyclooxygenase-2 Expression and Prostaglandin Release
Emerging evidence has established that astrocytes, once considered passive supporting cells that maintained extracellular ion… 
2010
2010
Live Cell Imaging Reveals Continuous STAT6 Nuclear Trafficking
The STAT6 transcription factor is essential for the development of protective immunity; however, the consequences of its activity… 
2010
2010
Active immune response protects Stat6VT transgenic mice from developing a lymphoproliferative disorder.
2008
2008
Treatment of cells with n-alpha-tosyl-L-phenylalanine-chloromethyl ketone induces the proteolytic loss of STAT6 transcription factor.
2008
2008
PTP 1 B is a negative regulator of interleukin 4 – induced STAT 6 signaling
Protein tyrosine phosphatase 1B (PTP1B) is a ubiquitously expressed enzyme shown to negatively regulate multiple tyrosine… 
2005
2005
Protein expression analysis of chromosome 12 candidate genes in chronic lymphocytic leukemia (CLL)
The pathogenic role of trisomy 12 in chronic lymphocytic leukemia (CLL) remains unresolved, but recently an upregulated RNA… 
2003
2003
Hepatocyte NF-1 and STAT6 Cooperate with Additional DNA-Binding Factors to Activate Transcription of the Human Polymeric Ig Receptor Gene in Response to IL-41
Secretory IgA and IgM, which protect the mucosal surfaces, are generated by selective transport of locally produced polymeric (p… 
1999
1999
Homologous human and murine antisense oligonucleotides targeting stat6. Functional effects on germline cepsilon transcript.
Interleukin (IL)-4 and (IL)-13 induce immunoglobulin (Ig)E synthesis via activation of the transcription factor signal transducer… 
Highly Cited
1997
Highly Cited
1997
Interleukin-4 suppression of tumor necrosis factor alpha-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-kappaB.
Interleukin-4 (IL-4), an immunoregulatory cytokine secreted from activated T-helper 2 lymphocytes, eosinophils, and mast cells… 
1996
1996
Purification and characterization of gene-specific transcription factors: C/EBP, GABP, and IL-4 stat.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)