STAT6 protein, human

Known as: signal transducer and activator of transcription 6 protein, human, Transcription Factor IL-4 STAT, Signal Transducer and Activator of Transcription 6 
Signal transducer and activator of transcription 6 (847 aa, ~94 kDa) is encoded by the human STAT6 gene. This protein is involved in the modulation… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
020406019942018

Papers overview

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Highly Cited
2013
Highly Cited
2013
A 44-year old woman with recurrent solitary fibrous tumor (SFT)/hemangiopericytoma was enrolled in a clinical sequencing program… (More)
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Highly Cited
2010
Highly Cited
2010
Peroxisome proliferator-activated receptor γ (PPARγ) is a lipid-activated transcription factor regulating lipid metabolism and… (More)
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Highly Cited
2006
Highly Cited
2006
Primary cilia are implicated in the pathogenesis of autosomal-dominant polycystic kidney disease (ADPKD), which results from… (More)
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Highly Cited
2004
Highly Cited
2004
Activation-induced cytidine deaminase (AID) is an inducible gene that plays an important role in class switch recombination… (More)
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Highly Cited
2002
Highly Cited
2002
STAT6 is a central mediator of IL-4-induced gene responses. STAT6-mediated transcription is depend ent on the C-terminal… (More)
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Highly Cited
2001
Highly Cited
2001
STAT transcription factors are expressed in many cell types and bind to similar sequences. However, different STAT gene knock… (More)
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Highly Cited
2000
Highly Cited
2000
Using a mouse model in which tumors show a growth-regression-recurrence pattern, we investigated the mechanisms for down… (More)
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Highly Cited
1999
Highly Cited
1999
Interferons (IFNs) inhibit induction by IL-4 of multiple genes in human monocytes. However, the mechanism by which IFNs mediate… (More)
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Highly Cited
1999
Highly Cited
1999
The C-C chemokine eotaxin is a potent chemoattractant for eosinophils and probably plays an important role in the pathogenesis of… (More)
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Highly Cited
1994
Highly Cited
1994
Interleukin-4 (IL-4) is an immunomodulatory cytokine secreted by activated T lymphocytes, basophils, and mast cells. It plays an… (More)
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