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SRY gene

Known as: SRY, TDF, Sex Determining Region Y Gene 
This gene is involved in testis development and may be involved in transcription.
National Institutes of Health

Related topics

Related topics

8 relations
Biologic DevelopmentHomo sapiensSex-Determining Region Y ProteinSexual Maturation

Broader (1)

Genes, sry

Narrower (1)

SRY wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
The mammalian Y chromosome acts as a dominant male determinant as a result of the action of a single gene, Sry, whose role in sex… 
Review
2007
Review
2007
Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors.
Review
2003
Review
2003
The molecular action and regulation of the testis-determining factors, SRY (sex-determining region on the Y chromosome) and SOX9 [SRY-related high-mobility group (HMG) box 9].
Despite 12 yr since the discovery of SRY, little is known at the molecular level about how SRY and the SRY-related protein, SOX9… 
Review
1997
Review
1997
Sox genes find their feet.
Review
1994
Review
1994
Molecular basis of mammalian sexual determination: activation of Müllerian inhibiting substance gene expression by SRY.
The pathway of male sexual development in mammals is initiated by SRY, a gene on the short arm of the Y chromosome. Its… 
Review
1993
Review
1993
SRY and sex determination in mammals.
INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 CLONING OF SRY… 
Highly Cited
1992
Highly Cited
1992
DNA binding activity of recombinant SRY from normal males and XY females.
The protein encoded by the human testis determining gene, SRY, contains a high mobility group (HMG) box related to that present… 
Highly Cited
1990
Highly Cited
1990
Genetic evidence equating SRY and the testis-determining factor
THE testis-determining factor gene (TDF) lies on the Y chromosome and is responsible for initiating male sex determination. SRY… 
Highly Cited
1990
Highly Cited
1990
Expression of a candidate sex-determining gene during mouse testis differentiation
THE development of a eutherian mammal as a male is a consequence of testis formation in the embryo, which is thought to be… 
Highly Cited
1990
Highly Cited
1990
A human XY female with a frame shift mutation in the candidate testis-determining gene SRY
THE primary decision about male or female sexual development of the human embryo depends on the presence of the Y chromosome1'2… 
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