Skip to search formSkip to main contentSkip to account menu

SPO11 protein, human

Known as: meiotic recombination protein SPO11, human, SPO11, SPO11 Protein Homolog 
Meiotic recombination protein SPO11 (396 aa, ~45 kDa) is encoded by the human SPO11 gene. This protein is involved in the modulation of chromosomal… 
National Institutes of Health

Related topics

Related topics

13 relations
Cell Cycle ControlCell NucleusDNA-Binding ProteinsGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Repair of protein-linked DNA double strand breaks: Using the adenovirus genome as a model substrate in cell-based assays.
2015
2015
[Association of SPO11 and GST gene polymorphisms with idiopathic male infertility in ethnic Han Chinese].
OBJECTIVE To explore the possible roles of polymorphisms of SPO11 and glutathionine S-transferase (GST) genes in idiopathic male… 
2013
2013
Molecular Determinants of Sporulation in Ashbya gossypii
Regulation of development and entry into sporulation is critical for fungi to ensure survival of unfavorable environmental… 
2011
2011
Detection of covalent DNA-bound Spo11 and topoisomerase complexes.
Topoisomerases can release topological stress and resolve DNA catenanes by a DNA strand breakage and re-ligation mechanism… 
Review
2009
Review
2009
Detection of SPO11-oligonucleotide complexes from mouse testes.
The SPO11 protein generates programmed DNA double-strand breaks (DSBs) that initiate meiotic recombination. Endonucleolytic… 
2007
2007
Targeted induction of meiotic double-strand breaks reveals chromosomal domain-dependent regulation of Spo11 and interactions among potential sites of meiotic recombination
Meiotic recombination is initiated by programmed DNA double-strand break (DSB) formation mediated by Spo11. DSBs occur with… 
2004
2004
Meiotic Chromosome Synapsis in Yeast Can Occur Without Spo11-Induced DNA Double-Strand Breaks
Proper chromosome segregation and formation of viable gametes depend on synapsis and recombination between homologous chromosomes… 
2004
2004
SPO11: une activité de coupure de l’ADN indispensable à la méiose
La recombinaison entre chromosomes homologues est un processus essentiel dont le role mecanique est d’assurer la segregation… 
2000
2000
Mouse homolog of Saccharomyces cerevisiae spo11 is induced in normal mu(+)B-cells by stimuli that cause germline C(H) transcription and subsequent class switch recombination.
The first step of Ig heavy chain class switch recombination (CSR) is considered to be DNA double strand break (DSB) formation in… 
1985
1985
Meiotic exchange within and between chromosomes requires a common Rec function in Saccharomyces cerevisiae
We used haploid yeast cells that express both the MATa and MAT alpha mating-type alleles and contain the spo13-1 mutation to… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)