H. Tokuyama

Publications28
h-index11
Citations349
Highly Influential Citations10
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Retinoids inhibit IL-4-dependent IgE and IgG1 production by LPS-stimulated murine splenic B cells.
The effects of retinoids (all-trans-retinoic acid (RA) and vitamin A) and hydrocortisone (HC) on the IL-4-dependent IgE and IgG1 response by mouse whole spleen cells and splenic B cells were studied.… Expand
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Endogenous cytokine expression profiles in retinoic acid-induced IgA production by LPS-stimulated murine splenocytes.
All-trans-retinoic acid (RA) enhances IgA production by LPS-stimulated murine splenocytes. After stimulation by RA and LPS, or by LPS alone, total RNA was extracted from cultured cells on Days 1 to… Expand
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Purification and identification of TGF-beta 2-related growth factor from bovine colostrum.
Bovine colostrum contains transforming growth factor (TGF)-beta-like activity. High levels of this activity are found in early colostrum (within 12 h after parturition); however, it decreases rapidly… Expand
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Retinoids enhance IgA production by lipopolysaccharide-stimulated murine spleen cells.
The effect of all-trans retinoic acid (RA) and vitamin A on IgA production by LPS-stimulated murine spleen cells was studied. Concentrations of immunoglobulins of six subclasses in the culture medium… Expand
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The regulatory effects of all-trans-retinoic acid on isotype switching: retinoic acid induces IgA switch rearrangement in cooperation with IL-5 and inhibits IgG1 switching.
All-trans-retinoic acid (RA) can induce germline Calpha transcription in LPS-stimulated murine mu(+)B-cells by a TGF-beta-independent mechanism. In the present study, we examined whether RA can… Expand
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Bovine colostric transforming growth factor-beta-like peptide that induces growth inhibition and changes in morphology of human osteogenic sarcoma cells (MG-63).
TGF-beta like peptide, termed TGF(BC-1), was partially purified from defatted and decaseinated bovine colostrum by a sequence of DEAE-Sephacel chromatography and Sephadex G-50 gel filtration in 1M… Expand
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Retinoic acid induces the expression of germ-line C alpha transcript mainly by a TGF-beta-independent mechanism.
The effects of retinoic acid (RA) on expression of germ-line transcripts, I alpha C alpha and I gamma 1C gamma 1, and of IgA and IgG1 mRNAs by murine surface IgM-positive B-cells were examined by… Expand
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Human cell membrane components dominant in T cell lineage: identification and characterization of human TL-like antigens.
Cell membrane components that contain beta 2-microglobulin were purified from cells of a human T cell-type leukemia cell line, HPB-ALL. They contained membrane components that have the same molecular… Expand
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ON THE ACTIVE SITE OF MYOSIN A-ADENOSINE TRIPHOSPHATASE. V. PARTIAL SOLUTION OF THE CHEMICAL STRUCTURE AROUND THE BINDING SITE OF TRINITROBENZENESULFONATE.
Abstract 1. 1. To clarify the chemical structures of the peptide chains of myosin A around the lysine residues, which are specifically attacked by trinitrobenzenesulfonate (TBS), myosin A, which… Expand
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Retinoic Acid Induces the Expression of Germ-Line Cα Transcript Mainly by a TGF-β-Independent Mechanism☆
Abstract The effects of retinoic acid (RA) on expression of germ-line transcripts, IαCα and Iγ1Cγ1, and of IgA and IgG1 mRNAs by murine surface IgM-positive B-cells were examined by reverse… Expand
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