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SPN protein, human

Known as: CD43, LSGP protein, human, Leukosialin 
Leukosialin (400 aa, ~40 kDa) is encoded by the human SPN gene. This protein is involved in immune cell function.
National Institutes of Health

Related topics

Related topics

16 relations
Antibacterial ResponseBlood coagulationCell Adhesion InhibitionChemotaxis

Broader (1)

CD43 Antigen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
CD43 Plays Both Antiadhesive and Proadhesive Roles in Neutrophil Rolling in a Context-Dependent Manner1
As the first step in the recruitment of neutrophils into tissues, the cells become tethered to and roll on the vessel wall. These… 
2006
2006
CD43 cross-linking increases the Fas-induced apoptosis through induction of Fas aggregation in Jurkat T-cells
CD43 (sialophorin, leukosialin) is a heavily sialylated surface protein expressed on most leukocytes and platelets including T… 
2003
2003
Chemotactically‐induced redistribution of CD43 as related to polarity and locomotion of human polymorphonuclear leucocytes
Highly Cited
2002
Highly Cited
2002
Dynamic Regulation of T Cell Immunity by CD431
During a viral response, Ag-specific effector T cells show dramatically increased binding by the mAb 1B11 and the lectin peanut… 
1998
1998
CD43 is associated with tyrosine kinase activity in human neutrophils
CD43 appears to be involved in signal transduction, however, the mechanism of this function is unknown. Protein kinase activity… 
1995
1995
Downregulation of Neutrophil CD43 by Opsonized Zymosan
CD43, a prevalent white blood cell molecule distinguished by its mucin- like surface region, has been proposed as a “functional… 
Highly Cited
1993
Highly Cited
1993
CD43, the major sialoglycoprotein of human leukocytes, is proteolytically cleaved from the surface of stimulated lymphocytes and granulocytes.
CD43, the major sialoglycoprotein of human leukocytes, whose expression is defective in patients with the Wiskott-Aldrich… 
1992
1992
Amino acid sequence of human plasma galactoglycoprotein: identity with the extracellular region of CD43 (sialophorin).
The amino acid sequence of galactoglycoprotein purified from human plasma was elucidated to 75% completeness by using chemical… 
1991
1991
cis-recognition and degradation of ornithine decarboxylase subunits in reticulocyte lysate.
One of the most interesting characteristics of ornithine decarboxylase (ODC) is its extremely short half-life. In a recent study… 
1985
1985
The large sialoglycoprotein of human lymphocytes. II. Biochemical features
Large sialoglycoprotein of human lymphocytes (L‐LSGP) from thymocytes and from peripheral blood lymphocytes (PBL) of normal donor… 
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