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CD43 Antigen

Known as: CD43, Antigen, CD43, Sialoglycoprotein, Leukocyte 
A sialic acid-rich protein and an integral cell membrane mucin. It plays an important role in activation of T-LYMPHOCYTES.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

CD Antigens
In BloodSPN geneaspects of radiation effectsphysiological aspects

Narrower (1)

SPN protein, human

Papers overview

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Highly Cited
2006
Highly Cited
2006
Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures.
During hematopoietic differentiation of human embryonic stem cells (hESCs), early hematopoietic progenitors arise along with… Expand
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Highly Cited
2001
Highly Cited
2001
Protection from Respiratory Virus Infections Can Be Mediated by Antigen-Specific Cd4+ T Cells That Persist in the Lungs
Although CD4+ T cells have been shown to mediate protective cellular immunity against respiratory virus infections, the… Expand
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Highly Cited
2001
Highly Cited
2001
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.
The large mucin CD43 is actively excluded from T cell/APC interaction sites, concentrating in a membrane domain distal to the… Expand
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Highly Cited
2000
Highly Cited
2000
Lack of CD 29 (beta1 integrin) and CD 54 (ICAM-1) adhesion molecules in intravascular lymphomatosis.
Intravascular Lymphomatosis (IL) is a rare and usually aggressive form of non-Hodgkin's lymphoma characterized by the growth of… Expand
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Highly Cited
1995
Highly Cited
1995
Negative regulation of T-cell adhesion and activation by CD43
CD43 is a cell-surface sialoglycoprotein expressed by a variety of haematopoietically derived cells, including T lymphocytes1á¤-9… Expand
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Highly Cited
1992
Highly Cited
1992
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells
P-selectin (CD62, GMP-140, PADGEM), a Ca(2+)-dependent lectin on activated platelets and endothelium, functions as a receptor for… Expand
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Highly Cited
1992
Highly Cited
1992
Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen.
A cDNA encoding UDP-GlcNAc:Gal beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase (EC 2.4.1.102), which forms… Expand
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Highly Cited
1991
Highly Cited
1991
CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1
THE protein CD43 (also known as sialophorin, leukosialin, large sialoglycoprotein or gp115) is expressed on the surface of T… Expand
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Highly Cited
1988
Highly Cited
1988
Induction of aggregation and enhancement of proliferation and IL-2 secretion in human T cells by antibodies to CD43.
CD43 (large sialoglycoprotein) is a heavily glycosylated protein expressed on virtually all thymus-derived lymphocytes, on a… Expand
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Highly Cited
1988
Highly Cited
1988
Human T-lymphocyte activation is associated with changes in O-glycan biosynthesis.
The activation of human T-lymphocytes by anti-CD3 antibodies and interleukin-2 results in a marked increase in apparent molecular… Expand
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