CD43 Antigen

Known as: CD43, Antigen, CD43, Sialoglycoprotein, Leukocyte 
A sialic acid-rich protein and an integral cell membrane mucin. It plays an important role in activation of T-LYMPHOCYTES.
National Institutes of Health

Related topics

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6 relations

Broader (1)

CD Antigens
In BloodSPN geneaspects of radiation effectsphysiological aspects

Narrower (1)

SPN protein, human

Papers overview

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Highly Cited
2006
Highly Cited
2006
Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures.
During hematopoietic differentiation of human embryonic stem cells (hESCs), early hematopoietic progenitors arise along with… (More)
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Highly Cited
2006
Highly Cited
2006
Galectin-1 binds different CD43 glycoforms to cluster CD43 and regulate T cell death.
Galectin-1 kills immature thymocytes and activated peripheral T cells by binding to glycans on T cell glycoproteins including CD7… (More)
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Highly Cited
2002
Highly Cited
2002
Dynamic regulation of T cell immunity by CD43.
During a viral response, Ag-specific effector T cells show dramatically increased binding by the mAb 1B11 and the lectin peanut… (More)
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Highly Cited
2001
Highly Cited
2001
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.
The large mucin CD43 is actively excluded from T cell/APC interaction sites, concentrating in a membrane domain distal to the… (More)
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Highly Cited
2001
Highly Cited
2001
Protection from Respiratory Virus Infections Can Be Mediated by Antigen-Specific Cd4+ T Cells That Persist in the Lungs
Although CD4(+) T cells have been shown to mediate protective cellular immunity against respiratory virus infections, the… (More)
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Highly Cited
1998
Highly Cited
1998
CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts.
Chemokines as well as the signaling through the adhesion molecules intercellular adhesion molecule (ICAM)-3 and CD43 are able to… (More)
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Highly Cited
1998
Highly Cited
1998
TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site.
CD43, a large highly glycosylated molecule, is arguably the most abundant molecule on the surface of T cells. Nevertheless, the… (More)
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Highly Cited
1995
Highly Cited
1995
Negative regulation of T-cell adhesion and activation by CD43
CD43 is a cell-surface sialoglycoprotein expressed by a variety of haematopoietically derived cells, including T lymphocytes1á¤-9… (More)
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Highly Cited
1994
Highly Cited
1994
CD43 (S7) expression identifies peripheral B cell subsets.
CD43 (leukosialin) expression has previously been demonstrated on the surface of developing B cells in mouse bone marrow and on… (More)
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Highly Cited
1991
Highly Cited
1991
CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1
THE protein CD43 (also known as sialophorin, leukosialin, large sialoglycoprotein or gp115) is expressed on the surface of T… (More)
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