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SPINT1 protein, human
Known as:
Hepatocyte Growth Factor Activator Inhibitor
, Hepatocyte Growth Factor Activator Inhibitor Type 1
, hepatocyte growth factor activator inhibitor 1, human
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Kunitz-type protease inhibitor 1 (529 aa, ~58 kDa) is encoded by the human SPINT1 gene. This protein plays a role in both growth factor signaling and…
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National Institutes of Health
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Related topics
Related topics
4 relations
Extracellular Space
Genes, Regulator
Regulation of Proteolysis
SPINT1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the ApcMin/+ model
M. Kawaguchi
,
Koji Yamamoto
,
+4 authors
H. Kataoka
OncoTarget
2016
Corpus ID: 43651271
Hepatocyte growth factor activator inhibitor type 1 (HAI-1), encoded by the Spint1 gene, is a membrane-bound serine protease…
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2011
2011
Epithelial and Mesenchymal Cell Biology Membrane-Bound Serine Protease Inhibitor HAI-1 Is Required for Maintenance of Intestinal Epithelial Integrity
M. Kawaguchi
,
N. Takeda
,
+7 authors
H. Kataoka
2011
Corpus ID: 2522632
From the Section of Oncopathology and Regenerative Biology, * Department of Pathology and the Department of Anatomy, Faculty of…
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2010
2010
Matriptase Does Not Require Hepatocyte Growth Factor Activator Inhibitor Type-1 for Activation in an Epithelial Cell Expression Model
Yuka Miyake
,
S. Tsuzuki
,
T. Fushiki
,
K. Inouye
Bioscience, biotechnology and biochemistry
2010
Corpus ID: 1697940
Matriptase is a type II transmembrane serine protease. Paradoxically, activation of this protease is thought to require its…
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2009
2009
Tissue injury alters the site of expression of hepatocyte growth factor activator inhibitor type 1 in bronchial epithelial cells
Hiroyuki Tanaka
,
T. Fukushima
,
K. Yorita
,
M. Kawaguchi
,
H. Kataoka
Human Cell
2009
Corpus ID: 22187212
Hepatocyte growth factor activator inhibitor-1 (HAI-1) is a Kunitz-type transmembrane serine proteinase inhibitor that inhibits…
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2008
2008
Expression of hepatocyte growth factor activator inhibitor type 1 on the epithelial cell surface is regulated by hypoxic and oxidative stresses
Wataru Komaki
,
T. Fukushima
,
Hiroyuki Tanaka
,
H. Itoh
,
E. Chosa
,
H. Kataoka
Virchows Archiv
2008
Corpus ID: 24971947
Hepatocyte growth factor activator inhibitor type 1 (HAI-1)/spint-1 is a membrane-bound protease inhibitor that is thought to…
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2007
2007
Roles of Kunitz domains in the anti-invasive effect of hepatocyte growth factor activator inhibitor type 1 in human glioblastoma cells
Shiro Miyata
,
T. Fukushima
,
K. Kohama
,
Hiroyuki Tanaka
,
H. Takeshima
,
H. Kataoka
Human Cell
2007
Corpus ID: 19214054
Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is a membrane-bound serine proteinase inhibitor having two…
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Highly Cited
2005
Highly Cited
2005
Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells.
Ming-Shyue Lee
,
K. Kiyomiya
,
Christelle Benaud
,
R. Dickson
,
Chen-Yong Lin
American Journal of Physiology - Cell Physiology
2005
Corpus ID: 7039298
Activation of single-chain, latent matriptase, a type II transmembrane serine protease, depends on the weak proteolytic activity…
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2005
2005
Diverse roles of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in the growth of glioblastoma cells in vivo.
Shiro Miyata
,
Shunro Uchinokura
,
+6 authors
H. Kataoka
Cancer Letters
2005
Corpus ID: 44709657
2001
2001
Expression of hepatocyte growth factor activator and hepatocyte growth factor activator inhibitor type 1 in human hepatocellular carcinoma.
Kenji Nagata
,
Shuichi Hirono
,
+8 authors
H. Tsubouchi
Biochemical and Biophysical Research…
2001
Corpus ID: 32231450
Hepatocyte growth factor activator inhibitor type 1 (HAI-1), a Kunitz-type serine protease inhibitor for hepatocyte growth factor…
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2001
2001
Mouse hepatocyte growth factor activator inhibitor type 1 (HAI-1) and type 2 (HAI-2)/placental bikunin genes and their promoters.
H. Itoh
,
H. Kataoka
,
J. Meng
,
R. Hamasuna
,
N. Kitamura
,
M. Koono
Biochimica et Biophysica Acta
2001
Corpus ID: 25236451
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