• Publications
  • Influence
Inhibition of gastric inhibitory polypeptide signaling prevents obesity
GIP directly links overnutrition to obesity and it is a potential target for anti-obesity drugs.
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.
The results suggest that FSP27 contributes to efficient energy storage in WAT by promoting the formation of unilocular lipid droplets, thereby restricting lipolysis and finding that the nature of lipid accumulation in Wat appears to be associated with maintenance of energy balance and insulin sensitivity.
Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase.
A series of results indicate that AQP7 disruption elevates adipose glycerol kinase activity, accelerates triglycerides synthesis in adipocytes, and, finally, develops obesity.
The Orosensory Recognition of Long-Chain Fatty Acids in Rats
These studies suggest that rats select LCFA from olfactory or gustatory cues that are related to both the carbon chain and carboxylate group.
Preference for corn oil in olfactory-blocked mice in the conditioned place preference test and the two-bottle choice test.
The results suggested that stimuli other than olfaction contributed to the rewarding effects of corn oil, but at lower concentrations olfactory stimuli might act as a signal for the oil.
Administration of Capsiate, a Non-Pungent Capsaicin Analog, Promotes Energy Metabolism and Suppresses Body Fat Accumulation in Mice
It is suggested that capsiate promotes energy metabolism and suppresses body fat accumulation as does capsaicin.
Importance of lipolysis in oral cavity for orosensory detection of fat.
  • T. Kawai, T. Fushiki
  • Chemistry, Medicine
    American journal of physiology. Regulatory…
  • 1 August 2003
Radioactive triolein applied on rats' circumvallate papilla revealed that lingual lipase was released continuously to generate significant amounts of fatty acids and other lipolytic products within 1-5 s, which was enough time to taste fat.
Possible involvement of the alpha1 isoform of 5'AMP-activated protein kinase in oxidative stress-stimulated glucose transport in skeletal muscle.
The data suggest that acute oxidative stress activates AMPKalpha1 in skeletal muscle via an AMP-independent mechanism and leads to an increase in the rate of glucose transport, at least in part, through an AM PKalpha1-mediated mechanism.