SPDEF gene

Known as: SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR, PROSTATE EPITHELIUM-SPECIFIC ETS TRANSCRIPTION FACTOR, PDEF 
This gene may be involved in prostate development and prostate cancer.
National Institutes of Health

Papers overview

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2015
2015
Epithelial cells that line the conducting airways provide the initial barrier and innate immune responses to the abundant… (More)
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2013
2013
Goblet cell numbers decrease within the conjunctival epithelium in drying and cicatrizing ocular surface diseases. Factors… (More)
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2013
2013
BACKGROUND & AIMS Expression of the SAM pointed domain containing ETS transcription factor (SPDEF or prostate-derived ETS factor… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND AND AIMS SPDEF (also termed PDEF or PSE) is an ETS family transcription factor that regulates gene expression in the… (More)
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2010
2010
Mucus hypersecretion is commonly observed in many chronic airway inflammatory diseases. Mucin 5AC (MUC5AC) is a major airway… (More)
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Highly Cited
2009
Highly Cited
2009
Various acute and chronic inflammatory stimuli increase the number and activity of pulmonary mucus-producing goblet cells, and… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND & AIMS Stem cells within the intestinal epithelium generate daughter cells that undergo lineage commitment and… (More)
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Highly Cited
2007
Highly Cited
2007
Goblet cell hyperplasia and mucous hypersecretion contribute to the pathogenesis of chronic pulmonary diseases including cystic… (More)
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Highly Cited
2006
Highly Cited
2006
Little is known of the underlying biology of estrogen receptor-negative, progesterone receptor-negative (ER(−)/PR(−)) breast… (More)
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Highly Cited
2000
Highly Cited
2000
Prostate cancer, the most frequent solid cancer in older men, is a leading cause of cancer deaths. Although proliferation and… (More)
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