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SPDEF gene

Known as: SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR, PROSTATE EPITHELIUM-SPECIFIC ETS TRANSCRIPTION FACTOR, PDEF 
This gene may be involved in prostate development and prostate cancer.
National Institutes of Health

Related topics

Related topics

5 relations
Cell Fate ControlHomo sapiensSAM Pointed Domain-Containing Ets Transcription FactorTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Research progress of SPDEF regulates asthmatic airway mucus hypersecretion
Bronchial asthma (asthma) is a chronic airway inflammatory disease involved by many cells and cellular components, whose main… 
2016
2016
98 SPDEF Shifts the Transcriptional Targets of Activated β-Catenin in Quiescent Intestinal Tumor Cells
2015
2015
Targeting FOXM1 auto-regulation in cancer
FOXM1 is an oncogenic transcription factor of the Forkhead family that is overexpressed in more than 20 types of human cancer.1… 
2012
2012
Role of SPDEF in Prostate Cancer
2011
2011
Loss of the Notch-ATOH1 Regulated Differentiation Factor, SPDEF, Increases Colon Tumor Number and Induces Local Invasion
2010
2010
Protein Kinase CK2 Controls the Stability of Prostate Derived ETS Factor
Prostate Derived ETS Factor (PDEF) is an ETS transcription factor expressed in prostate epithelial cells, and diminished PDEF… 
Review
2010
Review
2010
PDEF and PDEF-induced proteins as candidate tumor antigens for T cell and antibody-mediated immunotherapy of breast cancer
Novel breast tumor antigens are needed to develop T cell and antibody-based vaccine immunotherapy approach against breast cancer… 
2010
2010
Critical roles of Foxa2 and Spdef in regulating innate immunity and goblet cell differentiation in the lung
..........................................................................................................................................................1 Acknowledgements.........................................................................................................................................3 Table of 
2010
2010
Abstract 2251: Functional significance of prostate derived ETs factor in detection of highgrade prostate cancer
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC INTRODUCTION AND OBJECTIVES: Conventional… 
2009
2009
Proteomic analysis of a PDEF Ets transcription factor-interacting protein complex.
Ets proteins are a family of transcription factors that share an 85 amino acid conserved DNA binding domain, the ETS domain. The… 
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