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SOX2 Transcription Factor

Known as: SOX-2, Transcription Factor SOX-2, Transcription Factor, SOX2 
Transcription factor SOX-2 protein (317 aa, ~34 kDa) is encoded by the human SOX2 gene. This protein is involved in neural cell progenitor… 
National Institutes of Health

Related topics

Related topics

8 relations
Cell NucleusDNA-Binding ProteinsGenes, RegulatorSOX2 gene

Broader (1)

SOXB1 Transcription Factors

Papers overview

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2014
2014
Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model.
Highly Cited
2013
Highly Cited
2013
SOX2 overexpression correlates with poor prognosis in laryngeal squamous cell carcinoma.
Highly Cited
2012
Highly Cited
2012
Ontological Differences in First Compared to Third Trimester Human Fetal Placental Chorionic Stem Cells
Human mesenchymal stromal/stem cells (MSC) isolated from fetal tissues hold promise for use in tissue engineering applications… 
Highly Cited
2012
Highly Cited
2012
Generation of Induced Pluripotent Stem Cells from Human Renal Proximal Tubular Cells with Only Two Transcription Factors, Oct4 and Sox2*
Background: The generation of human-induced pluripotent stem cells (iPS) has raised expectations for disease modeling, drug… 
2012
2012
Identification of two novel phenotypically distinct breast cancer cell subsets based on Sox2 transcription activity.
Highly Cited
2010
Highly Cited
2010
Probing Stemness and Neural Commitment in Human Amniotic Fluid Cells
Recently, human amniotic fluid (AF) cells have attracted a great deal of attention as an alternative cell source for… 
Highly Cited
2010
Highly Cited
2010
SOX2 in Gastric Carcinoma, but not Hath1, is Related to Patients’ Clinicopathological Features and Prognosis
BackgroundSOX2 and Hath1 are transcription factors that are critical for the control of terminal cell differentiation in the… 
Review
2009
Review
2009
Evolution of non-coding regulatory sequences involved in the developmental process: Reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes
In higher vertebrates, the expression of Sox2, a group B1 Sox gene, is the hallmark of neural primordial cell state during the… 
2009
2009
ES Cell Extract‐Induced Expression of Pluripotent Factors in Somatic Cells
Reprogramming of somatic cells was induced by ES cell‐free extract. The system relied on the transient uptake of regulatory… 
2003
2003
The Co-activator p300 Associates Physically with and Can Mediate the Action of the Distal Enhancer of the FGF-4Gene*
Distal enhancers commonly regulate gene expression. However, the mechanisms of transcriptional mediation by distal enhancers… 
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