SOX2 Transcription Factor

Known as: SOX-2, Transcription Factor SOX-2, Transcription Factor, SOX2 
Transcription factor SOX-2 protein (317 aa, ~34 kDa) is encoded by the human SOX2 gene. This protein is involved in neural cell progenitor… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
MicroRNAs (miRNAs) are posttranscriptional modulators of gene expression and play an important role in many developmental… (More)
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Highly Cited
2009
Highly Cited
2009
Lineage-survival oncogenes are activated by somatic DNA alterations in cancers arising from the cell lineages in which these… (More)
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Highly Cited
2008
Highly Cited
2008
Ectopic expression of defined sets of genetic factors can reprogram somatic cells to induced pluripotent stem (iPS) cells that… (More)
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Highly Cited
2007
Highly Cited
2007
The pluripotency of embryonic stem (ES) cells is thought to be maintained by a few key transcription factors, including Oct3/4… (More)
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Highly Cited
2005
Highly Cited
2005
The transcription factors OCT4, SOX2, and NANOG have essential roles in early development and are required for the propagation of… (More)
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Highly Cited
2005
Highly Cited
2005
Nanog, Sox2, and Oct4 are transcription factors all essential to maintaining the pluripotent embryonic stem cell phenotype… (More)
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Highly Cited
2005
Highly Cited
2005
Embryonic stem cells (ESCs) are pluripotent cells that can either self-renew or differentiate into many cell types. Oct4 and Sox2… (More)
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Highly Cited
2003
Highly Cited
2003
Each cell lineage specified in the preimplantation mammalian embryo depends on intrinsic factors for its development, but there… (More)
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Highly Cited
2003
Highly Cited
2003
Neural progenitors of the vertebrate CNS are defined by generic cellular characteristics, including their pseudoepithelial… (More)
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Highly Cited
2003
Highly Cited
2003
A submicroscopic deletion containing SOX2 was identified at the 3q breakpoint in a child with t(3;11)(q26.3;p11.2) associated… (More)
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