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SOX2 gene

Known as: SOX2, SRY-box 2, SRY-RELATED HMG-BOX GENE 2 
This gene is involved in embryonic development and in the determination of cell fate.
National Institutes of Health

Related topics

Related topics

6 relations
Embryonic InductionHomo sapiensSOX2 Transcription FactorSOX2-OT gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Coagulation factor 2 thrombin receptor promotes malignancy in glioma under SOX2 regulation
Glioma is the most common human primary brain cancer with high mortality and unfavorable clinical outcome. Coagulation factor 2… 
2019
2019
Differential expression of claudin‑4, occludin, SOX2 and proliferating cell nuclear antigen between basaloid squamous cell carcinoma and squamous cell carcinoma.
Basaloid squamous cell carcinomas (BSCCs) in oral lesions are extremely rare, and the histology is not well understood… 
2019
2019
MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Maternal embryonic leucine zipper kinase (MELK) has been reported to serve critical roles in the maintenance of stemness of… 
2019
2019
Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle
2019
2019
Effects of ten-eleven translocation 1 (Tet1) on DNA methylation and gene expression in chicken primordial germ cells.
Ten-eleven translocation 1 (Tet1) is involved in DNA demethylation in primordial germ cells (PGCs); however, the precise… 
2018
2018
Betulinic acid inhibits stemness and EMT of pancreatic cancer cells via activation of AMPK signaling
Cancer stem cells (CSCs), which are found in various types of human cancer, including pancreatic cancer, possess elevated… 
2017
2017
Effect of SOX2 on odontoblast differentiation of dental pulp stem cells.
The present study aimed to investigate the effect of SOX2 on odontoblast differentiation of dental pulp stem cells (DPSCs), and… 
2016
2016
MicroRNA-21 promotes migration and invasion of glioma cells via activation of Sox2 and β-catenin signaling
The expression of microRNA 21 (miR-21) has been reported to be upregulated in various types of cancer, including malignant… 
2016
2016
Gene mapping in an anophthalmic pedigree of a consanguineous Pakistani family opened new horizons for research
ABSTRACT Clinical anophthalmia is a rare inherited disease of the eye and phenotype refers to the absence of ocular tissue in the… 
2011
2011
Evaluation of Sox2 genetic effect on the development of type 2 diabetes.
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