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SOX2-OT gene

Known as: non-protein coding RNA 43, NONCODING RNA 43, SOX2-OT 
 
National Institutes of Health

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SOX2 gene

Papers overview

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Highly Cited
2018
Highly Cited
2018
Tumor-derived exosomal lnc-Sox2ot promotes EMT and stemness by acting as a ceRNA in pancreatic ductal adenocarcinoma
Long noncoding RNAs (lncRNAs) or exosomes have recently been shown to play vital regulatory or communication roles in cancer… Expand
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Highly Cited
2017
Highly Cited
2017
Knockdown of SOX2OT inhibits the malignant biological behaviors of glioblastoma stem cells via up-regulating the expression of miR-194-5p and miR-122
BackgroundAccumulating evidence has highlighted the potential role of long non-coding RNAs (lncRNAs) in the biological behaviors… Expand
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Highly Cited
2016
Highly Cited
2016
LncRNA Sox2ot overexpression serves as a poor prognostic biomarker in gastric cancer.
Sox2 overlapping transcript (Sox2ot) serves as an unfavorable prognostic factor in lung cancer and hepatocellular carcinoma, but… Expand
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2016
2016
Long Noncoding RNA-Sox2OT Knockdown Alleviates Diabetes Mellitus-Induced Retinal Ganglion Cell (RGC) injury
Retinal ganglion cell (RGC) injury is one of the important pathological features of diabetes-induced retinal neurodegeneration… Expand
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Highly Cited
2015
Highly Cited
2015
Expression analysis of four long noncoding RNAs in breast cancer
Breast cancer is a molecularly heterogeneous disease which necessitates a search for markers to provide a more specific… Expand
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2015
2015
Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis.
BACKGROUND Long non-coding RNAs (lncRNAs) have been shown to have important regulatory roles in cancer biology, and the lncRNA… Expand
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Highly Cited
2014
Highly Cited
2014
Emerging Role of Long Non-Coding RNA SOX2OT in SOX2 Regulation in Breast Cancer
The transcription factor SOX2 is essential for maintaining pluripotency in a variety of stem cells. It has important functions… Expand
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Highly Cited
2014
Highly Cited
2014
Two novel splice variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are coupregulated with SOX2 and OCT4 in esophageal squamous cell carcinoma.
Long noncoding RNAs (lncRNAs) have emerged as new regulators of stem cell pluripotency and tumorigenesis. The SOX2 gene, a master… Expand
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Highly Cited
2014
Highly Cited
2014
A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival.
  • Z. Hou, W. Zhao, +10 authors J. Yan
  • The international journal of biochemistry & cell…
  • 2014
    • Corpus ID: 34341978
Sox2 overlapping transcript (Sox2ot) is a long noncoding RNA (lncRNA), localized on human chromosome 3q26.33, which is frequently… Expand
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Highly Cited
2009
Highly Cited
2009
Complex architecture and regulated expression of the Sox2ot locus during vertebrate development.
The Sox2 gene is a key regulator of pluripotency embedded within an intron of a long noncoding RNA (ncRNA), termed Sox2… Expand
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