SOD1 gene

Known as: Superoxide Dismutase 1, Soluble (Amyotrophic Lateral Sclerosis 1 (Adult)) Gene, SUPEROXIDE DISMUTASE, SOLUBLE, SUPEROXIDE DISMUTASE, COPPER-ZINC 
This gene plays a role in the detoxification of superoxide radicals in the cytosol.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
0102019852017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Neurodegeneration in an inherited form of ALS is non-cell-autonomous, with ALS-causing mutant SOD1 damage developed within… (More)
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Highly Cited
2008
Highly Cited
2008
The antioxidant enzyme superoxide dismutase 1 (SOD1) is a critical player of the antioxidative defense whose activity is altered… (More)
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Highly Cited
2007
Highly Cited
2007
Recently, 43-kDa TAR DNA-binding protein (TDP-43) was identified as a component of ubiquitinated inclusions (UIs) in sporadic… (More)
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Highly Cited
2007
Highly Cited
2007
Misfolding of Cu/Zn-superoxide dismutase (SOD1) is emerging as a mechanism underlying motor neuron degeneration in individuals… (More)
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Highly Cited
2007
Highly Cited
2007
Here we report an in vitro model system for studying the molecular and cellular mechanisms that underlie the neurodegenerative… (More)
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2006
2006
PURPOSE To screen superoxide dismutase 1 (SOD1) on chromosome 21 as a possible candidate gene for familial keratoconus (KC… (More)
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Highly Cited
2005
Highly Cited
2005
A "gain-of-function" toxic property of mutant Cu-Zn superoxide dismutase 1 (SOD1) is involved in the pathogenesis of some… (More)
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Highly Cited
2002
Highly Cited
2002
Familial amyotrophic lateral sclerosis (FALS)-linked mutations in copper-zinc superoxide dismutase (SOD1) cause motor neuron… (More)
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1999
1999
Transgenic mice that express a mutant Cu/Zn superoxide dismutase (SOD1) gene have been provided a valuable model for human… (More)
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1996
1996
All mutations in the SOD1 gene associated with familial ALS behave as dominant traits. One mutation, however, giving rise to an… (More)
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