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SOCS3 gene

Known as: Suppressor of Cytokine Signaling 3 Gene, CIS3, SOCS3 
This gene is involved in the regulation of cytokine-mediated signaling.
National Institutes of Health

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Related topics

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Cytokine SignalingGrowthHomo sapiensInterferon Signaling Process

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SOCS3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B
The clinical manifestations of hepatitis B viral infection (HBV) include chronic hepatitis B (CHB), liver cirrhosis (LC) and… 
2016
2016
SOCS3 induces neurite differentiation and promotes neuronal cell survival
Cytokines and growth factors play an important role in neuronal survival as well as cell death. The family of suppressors of… 
2014
2014
SOCS3 Promoter Hypermethylation Is a Favorable Prognosticator and a Novel Indicator for G-CIMP-Positive GBM Patients
Background Hypermethylation of the suppressor of cytokine signaling 3(SOCS3) promoter has been reported to predict a poor… 
Review
2013
Review
2013
SOCS3
SOCS3 is an inducible negative feedback inhibitor of cytokine signaling. Conditional deletion of SOCS3 in mice using the Cre-lox… 
2011
2011
A pivotal role for antigen-presenting cells overexpressing SOCS3 in controlling invariant NKT cell responses during collagen-induced arthritis
Objective Suppressor of cytokine signalling (SOCS) proteins constitute a class of intracellular proteins that are key… 
2006
2006
Overexpression of SOCS3 is associated with decreased survival in a cohort of patients with de novo follicular lymphoma
The prognostic significance of SOCS3 protein expression was determined in de novo follicular lymphomas (FL) with t(14;18) and bcl… 
Highly Cited
2005
Highly Cited
2005
Genetic reduction of embryonic leukemia-inhibitory factor production rescues placentation in SOCS3-null embryos but does not prevent inflammatory disease.
The suppressor of cytokine-signaling (SOCS) proteins act as negative-feedback inhibitors of cytokine and growth-factor-induced… 
2005
2005
Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during acute inflammatory processes in vivo.
2001
2001
Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 Is Involved in gp130 Resistance in Cardiovascular System in Rat Treated With Cardiotrophin-1 In Vivo
CIS (cytokine-inducible SH2 protein), SOCS (suppressor of cytokine signaling), or SSI (signal transducers and activators of… 
1993
1993
Comparison of a DNA hybridization probe and ELISA for the detection of Clavibacter michiganensis subsp. sepedonicus in field-grown potatoes
Clavibacter michiganensis subsp. sepedonicus, the causal agent of bacterial ring rot, was detected in field-grown potatoes using… 
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