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SOCS3 gene

Known as: Suppressor of Cytokine Signaling 3 Gene, CIS3, SOCS3 
This gene is involved in the regulation of cytokine-mediated signaling.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Hypothalamic leptin resistance is found in most common forms of obesity, such as diet-induced obesity, and is… 
Highly Cited
2006
Highly Cited
2006
Suppressor of cytokine signaling (Socs) 3 is a cytokine-inducible inhibitor with critical but selective cell-specific effects. We… 
Highly Cited
2005
Highly Cited
2005
ABSTRACT Cytokine responses can be regulated by a family of proteins termed suppressors of cytokine signaling (SOCS) which can… 
Highly Cited
2003
Highly Cited
2003
The suppressors of cytokine signaling (SOCS) are negative feedback inhibitors of cytokine and growth factor-induced signal… 
Highly Cited
2003
Highly Cited
2003
The suppressor of cytokine signaling-3 (SOCS3/CIS-33/SSI-3) is an important negative regulator of cytokine signaling. Here, we… 
Highly Cited
2001
Highly Cited
2001
Immune and inflammatory systems are controlled by multiple cytokines, including ILs and INFs. These cytokines exert their… 
Highly Cited
2000
Highly Cited
2000
The cytokine-inducible SH2 protein-3 (CIS3/SOCS-3/SSI-3) has been shown to inhibit the JAK/STAT pathway and act as a negative… 
Highly Cited
1999
Highly Cited
1999
Highly Cited
1999
The Janus family of protein tyrosine kinases (JAKs) regulate cellular processes involved in cell growth, differentiation and…