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SLC7A8 wt Allele

Known as: Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 Gene, LAT2, LPI-PC1 
Human SLC7A8 wild-type allele is located in the vicinity of 14q11.2 and is approximately 58 kb in length. This allele, which encodes large neutral… 
National Institutes of Health

Related topics

Related topics

6 relations
14q11.2Homo sapiensIonophore activityLigand Binding

Papers overview

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2019
2019
Effects of astragalus injection on different stages of early hepatocarcinogenesis in a two-stage hepatocarcinogenesis model using rats
To clarify the suppressive effects of astragalus injection (AI) on different stages of early hepatocarcinogenesis induced by weak… 
2019
2019
Molecular Mechanisms of Thyroid Hormone Transport by l-Type Amino Acid Transporter.
Thyroid hormones (TH) pass through the plasma membrane into the target cells via transporter proteins. Thyroid hormone… 
2017
2017
18F-FBPA as a tumor-specific probe of L-type amino acid transporter 1 (LAT1): a comparison study with 18F-FDG and 11C-Methionine PET
PurposeThe purpose of this study was to evaluate the usefulness of L-4-borono-2-18F-fluoro-phenylalanine (18F-FBPA) as a tumor… 
2017
2017
Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma
Na-independent large neutral amino acid transporters (LATs) represent the main intracellular transport route for several… 
2011
2011
Regulation of the adaptor molecule LAT2, an in vivo target gene of AML1/ETO (RUNX1/RUNX1T1), during myeloid differentiation
The leukaemia‐specific fusion oncoprotein RUNX1/RUNX1T1 (AML1/ETO), resulting from the chromosomal translocation (8;21) in acute… 
2008
2008
Genomic regulation of intestinal amino acid transporters by aldosterone
Overexpression of renal LAT2, a Na+-independent l-amino acid transporter, in spontaneous hypertensive rats (SHR) is organ… 
2007
2007
Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan
Objectives Melphalan is widely used in the treatment of multiple myeloma. Pharmacokinetics of this alkylating drug shows high… 
2007
2007
Localization of the System L Amino Acid Transporters LAT1 and LAT2 in Rat Gastrointestinal Tract
System L amino acid transporters LAT1 and LAT2 are the members of SLC7 amino acid transporter family. They link to their… 
2004
2004
High-and low-affinity transport of L-leucine and L-DOPA by the hetero amino acid exchangers LAT 1 and LAT 2 in LLC-PK 1 renal cells
Soares-da-Silva, Patrı́cio, and Maria Paula Serrão. Highand low-affinity transport of L-leucine and L-DOPA by the hetero amino… 
Highly Cited
2003
Highly Cited
2003
Asymmetry of glutamine transporters in cultured neural cells
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