SLC47A2 gene

Known as: MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2, Solute Carrier Family 47 (Multidrug and Toxin Extrusion), Member 2 Gene, MATE2-K 
This gene is involved in excretion of toxic electrolytes.
National Institutes of Health

Related topics

Related topics

8 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport
(More)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine.
The antiviral lamivudine is cleared predominantly by the kidney with a relevant contribution of renal tubular secretion. It is… (More)
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug…
Cimetidine, an H₂ receptor antagonist, has been used to investigate the tubular secretion of organic cations in human kidney. We… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2012
2012
Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis.
BACKGROUNDS AND PURPOSE Lactic acidosis is a fatal adverse effect of metformin, but the risk factor remains unclear. Multidrug… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
2012
2012
Anther extrusion and plant height are associated with Type I resistance to Fusarium head blight in bread wheat line ‘Shanghai-3/Catbird’
Fusarium head blight (FHB) is a destructive wheat disease of global importance. Resistance breeding depends heavily on the Fhb1… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2011
Highly Cited
2011
MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.
The majority of flavonoids, such as anthocyanins, proanthocyanidins, and isoflavones, are stored in the central vacuole, but the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
2011
2011
Prediction of fluoroquinolone-induced elevation in serum creatinine levels: a case of drug-endogenous substance interaction involving the inhibition of renal secretion.
The aim of this study was to examine the mechanism underlying the elevation in serum creatinine levels caused by a novel des… (More)
Is this relevant?
2011
2011
Characterization of the human MATE2 proton-coupled polyspecific organic cation exporter.
Human multidrug and toxic compound extrusion 2 (hMATE2) is a kidney-specific isoform of hMATE1, an exporter of toxic organic… (More)
Is this relevant?
2008
2008
Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice.
Transporters are expressed in a wide variety of tissues where they perform the critical function of enabling anionic and cationic… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
2007
2007
Molecular identification and functional characterization of rabbit MATE1 and MATE2-K.
An electroneutral organic cation (OC)/proton exchanger in the apical membrane of proximal tubules mediates the final step of… (More)
Is this relevant?
2006
2006
Meniscal extrusion in young athletes: associated knee joint abnormalities.
OBJECTIVE The objective of our study was to assess the rate of meniscal extrusion and its connection with common meniscal and… (More)
Is this relevant?